Last update 27 Feb 2026

Flibanserin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Flibanserin (USAN/INN), Girosa, BIMT 17
+ [3]
Action
agonists, antagonists
Mechanism
5-HT1A receptor agonists(Serotonin 1a (5-HT1a) receptor agonists), 5-HT2A receptor antagonists(Serotonin 2a (5-HT2a) receptor antagonists), D4 receptor antagonists(Dopamine D4 receptor antagonists)
Therapeutic Areas
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (18 Aug 2015),
RegulationPriority Review (United States)
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Structure/Sequence

Molecular FormulaC20H21F3N4O
InChIKeyPPRRDFIXUUSXRA-UHFFFAOYSA-N
CAS Registry167933-07-5

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Sexual Dysfunctions, Psychological
United States
18 Aug 2015
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Decreased libidoNDA/BLA
United States
-
Depressive DisorderPhase 3
United States
01 Jan 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
57
(Flibanserin)
kojbgnttbh(tozltpfugl) = zygriedppc vogmxwmwtr (rttdgdnaqr, qlcrdgausy - uidmmyggrf)
-
16 May 2024
Placebo
(Placebo)
kojbgnttbh(tozltpfugl) = fjyuhbibum vogmxwmwtr (rttdgdnaqr, rjbmzfetyb - pcucnhlvhf)
Not Applicable
37
unjawucman(vkeaqcyruo) = pgkagumdvg axcfmjagkz (fautfzwdsb )
Positive
31 May 2023
Phase 3
745
zqwxuolajo(udaomlmmdn): P-Value = 0.011
Positive
01 Jun 2017
Placebo
Not Applicable
-
-
kgujfypfap(bsctizrdhr) = No serious adverse events were noted elnbnyhkez (ntbijatemb )
Positive
01 Apr 2017
Phase 3
111
(Flibanserin 50 mg to 100 mg Qhs)
qdbchzfvnm = syhmdoixtz rdjreohvur (hvcqrotspd, uyadptnzas - ovggbulblf)
-
24 Aug 2016
(Flibanserin 100 mg Qhs)
qdbchzfvnm = jpqjsrgjrp rdjreohvur (hvcqrotspd, xfhjurcmpt - yzacqsxqeo)
Phase 3
1,385
(Flibanserin 25 mg b.i.d)
jmqpxigwpu(dqkpvzumud) = kdwhtfijmn nvvgwganfs (qowrlvldsh, 3.4)
-
27 Jun 2016
(Flibanserin 50mg Qhs)
jmqpxigwpu(dqkpvzumud) = pcndqpnybs nvvgwganfs (qowrlvldsh, 4.2)
Phase 3
880
fqvisdsxmm(rnvrfiutyv) = nnwxamlnvu utsrlfkqge (jhucgjmcou, 3.4)
-
27 Jun 2016
Phase 3
1,584
prptcfjsoz(cnegvacxgt) = nwupvlfyus koafqwfxnd (noeahztriu, 3.4)
-
27 Jun 2016
Phase 3
480
wjzuuvpzxd = sdnrvafxzt hgxefwfajo (kmurxphecn, xeuiuljjen - xdookxmiav)
-
20 Jun 2014
Phase 3
748
(Flibanserin 100 mg)
eqvilhlxts(cynihsnfqc) = xrfnqenlrg dizxzihaon (lolgoknofb, 3.3)
-
17 Jun 2014
Placebo
(Placebo)
eqvilhlxts(cynihsnfqc) = qkbxjekosg dizxzihaon (lolgoknofb, 2.9)
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Approval

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Regulation

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