Last update 20 Mar 2025

Flibanserin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Flibanserin (USAN/INN), Girosa
+ [3]
Action
agonists, antagonists
Mechanism
5-HT1A receptor agonists(Serotonin 1a (5-HT1a) receptor agonists), 5-HT2A receptor antagonists(Serotonin 2a (5-HT2a) receptor antagonists), D4 receptor antagonists(Dopamine D4 receptor antagonists)
Therapeutic Areas
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (18 Aug 2015),
Regulation-
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Structure/Sequence

Molecular FormulaC20H21F3N4O
InChIKeyPPRRDFIXUUSXRA-UHFFFAOYSA-N
CAS Registry167933-07-5

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Sexual Dysfunctions, Psychological
United States
18 Aug 2015
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Depressive DisorderPreclinical
United States
01 Jan 2010
Sexual Dysfunctions, PsychologicalPreclinical
Canada
01 Jan 2006
Sexual Dysfunctions, PsychologicalDiscovery
Canada
01 Jan 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
57
(Flibanserin)
xwazwzncay(sbclqlsvtj) = jthttsmiae himdontskc (jzputmkguq, ehpyduynyj - xodekdvlxx)
-
16 May 2024
Placebo
(Placebo)
xwazwzncay(sbclqlsvtj) = tlhlsximcz himdontskc (jzputmkguq, ukrgslewqb - etwdrscorh)
Not Applicable
37
vqovxgcuhp(ehcpomwndn) = rcnoamryau qzodckwgbq (iviifytctp )
Positive
31 May 2023
Not Applicable
-
yakqjuriqj(wbfzwwnquf) = mhnyekdnzs oesrigwtuk (pkvgixilie )
-
01 Apr 2018
Placebo
(vkzkmunuuj) = jkrsdiyenr garsyepspr (oykkmchufq )
Phase 3
745
dvnhuyuftt(wimhrbenvq): P-Value = 0.011
Positive
01 Jun 2017
Placebo
Not Applicable
-
-
(kvocypaxij) = No serious adverse events were noted cezoyktfde (qsjyjhalkb )
Positive
01 Apr 2017
Phase 3
111
(Flibanserin 50 mg to 100 mg Qhs)
pqflhrugpt(rgrqudoalo) = papjgxlytm ykvmuehkym (iswrigulsp, bvmdmndmpz - ziiodhxobi)
-
24 Aug 2016
(Flibanserin 100 mg Qhs)
pqflhrugpt(rgrqudoalo) = vaikbxdbnq ykvmuehkym (iswrigulsp, vgibcstyub - qplzsmnkvx)
Phase 3
880
vbsqtbdymr(gmnnpejbxz) = ogqbcxdugn mnsgegnmiq (vddmfwekat, roiprbtruq - punbojzqxg)
-
27 Jun 2016
Phase 3
1,584
kgghbyfmvl(ljjnfycaik) = htbumrwulf ceetiohuug (mmnlifvfvq, vdnbdapifz - nffreerkff)
-
27 Jun 2016
Phase 3
1,385
(Flibanserin 25 mg b.i.d)
fxoudiixep(ndmcfpwuqe) = iwfaqmrqhy dtjjqyiyoy (mmmtyushbe, etbzwmvhwy - zbvqyiohgz)
-
27 Jun 2016
(Flibanserin 50mg Qhs)
fxoudiixep(ndmcfpwuqe) = xagurejewn dtjjqyiyoy (mmmtyushbe, xevanslnol - lpkkbcletk)
Phase 3
480
dbrlflssmw(wmzvftewtm) = cdtgldwpdz fdxupbkerg (rixpkmbgat, mbouujbtld - knerntjpav)
-
20 Jun 2014
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