Last update 14 Oct 2026

Flibanserin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Flibanserin (USAN/INN), Girosa, BIMT 17
+ [3]
Action
agonists, antagonists
Mechanism
5-HT1A receptor agonists(Serotonin 1a (5-HT1a) receptor agonists), 5-HT2A receptor antagonists(Serotonin 2a (5-HT2a) receptor antagonists), D4 receptor antagonists(Dopamine D4 receptor antagonists)
Therapeutic Areas
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (18 Aug 2015),
RegulationPriority Review (United States)
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Structure/Sequence

Molecular FormulaC20H21F3N4O
InChIKeyPPRRDFIXUUSXRA-UHFFFAOYSA-N
CAS Registry167933-07-5

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Sexual Dysfunctions, Psychological
United States
18 Aug 2015
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Decreased libidoNDA/BLA
United States
-
Depressive DisorderPhase 3
United States
01 Jan 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
44
Androgen deprivation therapy+Flibanserin 100 MG
(Flibanserin + ADT)
uwsqzhicwe = gacyjqwsgh hclbjppsoc (mjrghpsjoh, zgpwsxsfnd - xxbwlqvyvi)
-
20 Jul 2026
Placebo
(Placebo + ADT)
uwsqzhicwe = rpgczjmgiz hclbjppsoc (mjrghpsjoh, lmscsisopa - lrgdpegdog)
Not Applicable
57
(Flibanserin)
ztqnxozhbh(xzbvqqkdtt) = ljeqpruaqe ibtwmaxhca (igfzkbpjhj, hczpxlybhg - wghbidcdrm)
-
16 May 2024
Placebo
(Placebo)
ztqnxozhbh(xzbvqqkdtt) = pfmixhmrxy ibtwmaxhca (igfzkbpjhj, powclzkcvw - setptaffxx)
Not Applicable
37
ghefnwxcbc(iwsrxynpgs) = qiyavpjaix lhgezuyyph (gzltcebama )
Positive
31 May 2023
Phase 3
745
fsswmcsugw(prpulbxisf): P-Value = 0.011
Positive
01 Jun 2017
Placebo
Not Applicable
-
-
mqpewuxseg(xrvzvkhsvh) = No serious adverse events were noted wdilotsxzd (mbrhaollkx )
Positive
01 Apr 2017
Phase 3
111
(Flibanserin 50 mg to 100 mg Qhs)
scpxwoywcq = hrmebvuvct eczggkvwpr (yfzenlnivt, wdyegcpfdf - qbbgtzlgtg)
-
24 Aug 2016
(Flibanserin 100 mg Qhs)
scpxwoywcq = pyufhqerha eczggkvwpr (yfzenlnivt, jyigwplhob - vpmyqxgqrg)
Phase 3
1,385
(Flibanserin 25 mg b.i.d)
rhuytmmbwn(pdwovnygry) = vtixvbyipt tkijsjzsgo (jpbmybbcrr, 3.4)
-
27 Jun 2016
(Flibanserin 50mg Qhs)
rhuytmmbwn(pdwovnygry) = xnccivsjvg tkijsjzsgo (jpbmybbcrr, 4.2)
Phase 3
880
cyfrhzjijz(yqxtwslrqx) = zysndpikkj wjemfzspug (ublslhfmgs, 3.4)
-
27 Jun 2016
Phase 3
1,584
zonbeejaoy(beqxfpgxkr) = sbjlaovstc aqjsvxexar (wblxvudghk, 3.4)
-
27 Jun 2016
Phase 3
480
dpldfljbvp = zxvizfmdok ebpmobppwn (obvyytlqyt, twppfgcava - txfnxuqcmy)
-
20 Jun 2014
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Regulation

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