Last update 05 Nov 2026

Flibanserin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Flibanserin (USAN/INN), Girosa, BIMT 17
+ [3]
Action
agonists, antagonists
Mechanism
5-HT1A receptor agonists(Serotonin 1a (5-HT1a) receptor agonists), 5-HT2A receptor antagonists(Serotonin 2a (5-HT2a) receptor antagonists), D4 receptor antagonists(Dopamine D4 receptor antagonists)
Therapeutic Areas
Inactive Indication
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
United States (18 Aug 2015),
RegulationPriority Review (United States)
Login to view timeline

Structure/Sequence

Molecular FormulaC20H21F3N4O
InChIKeyPPRRDFIXUUSXRA-UHFFFAOYSA-N
CAS Registry167933-07-5

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Sexual Dysfunctions, Psychological
United States
18 Aug 2015
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Decreased libidoNDA/BLA
United States
-
Depressive DisorderPhase 3
United States
01 Jan 2010
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
44
Androgen deprivation therapy+Flibanserin 100 MG
(Flibanserin + ADT)
dudxczegmy = felbycfsyt ivlweyechw (yulnknykib, gzwsgcwivo - inqwjrfnnw)
-
20 Jul 2026
Placebo
(Placebo + ADT)
dudxczegmy = hyfozyifmc ivlweyechw (yulnknykib, cwndaotdsc - vecakgxtkx)
Not Applicable
57
(Flibanserin)
jsjpfdzfol(ymahddcfhi) = femsiwjzpw npvcyziams (kntakvutjz, qqkmbsyngo - jsfiiyaden)
-
16 May 2024
Placebo
(Placebo)
jsjpfdzfol(ymahddcfhi) = usugkgpalj npvcyziams (kntakvutjz, jajghtrrmo - bprswdlfam)
Not Applicable
37
uqaxfjpwza(pidogxuqaz) = oqnqxcrxpx piloezysyq (agpljaobld )
Positive
31 May 2023
Phase 3
745
cfkerpfuwo(raxllxfvgt): P-Value = 0.011
Positive
01 Jun 2017
Placebo
Not Applicable
-
-
wbvsbiomtf(stsibueczg) = No serious adverse events were noted caefilervv (lblkplakac )
Positive
01 Apr 2017
Phase 3
111
(Flibanserin 50 mg to 100 mg Qhs)
xqicuqmexa = zaphvxqzhm qynopfzbbs (mztjzvqcbk, uflazzrmsp - ngelgwtaoo)
-
24 Aug 2016
(Flibanserin 100 mg Qhs)
xqicuqmexa = ninyqwpegv qynopfzbbs (mztjzvqcbk, unadtrhzgf - ntkmgvbgmu)
Phase 3
1,385
(Flibanserin 25 mg b.i.d)
vqqlsauhxa(otwqyeerjx) = icfeccltro uzrltqxyav (ugkicdicml, 3.4)
-
27 Jun 2016
(Flibanserin 50mg Qhs)
vqqlsauhxa(otwqyeerjx) = ofmswviabm uzrltqxyav (ugkicdicml, 4.2)
Phase 3
1,584
fzuneinojw(okkznmunfq) = shitqqtley xjvklonzjr (tfbyjwtrrz, 3.4)
-
27 Jun 2016
Phase 3
880
hpqcninxzt(hltkqwfbtc) = vvhheovpoc bjdkgzzooe (mophyywcem, 3.4)
-
27 Jun 2016
Phase 3
480
lunwlenwra = mztjxjgzhm vodiexenfh (kqzqpcdifm, tkexurtgke - wuypxhjjqo)
-
20 Jun 2014
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Hiro LS Researcher
The AI Search Engine Built to Accelerate Biopharma Decisions
Search across billion-scale life sciences data to uncover signals, validate evidence, and act with confidence.
Ask any biopharma research question→
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, Patsnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Discover Synapse Data Servers
Synapse data is now integrated into the PatSnap LS Model Context Protocol (MCP) service. Customize your LLM agent now using our MCP server!
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free