Last update 05 Jul 2025

Anti-mesothelin CAR-T cell therapy (Tmunity Therapeutics/University of Pennsylvania)

Overview

Basic Info

Drug Type
CAR-T
Synonyms
AntiMSLN CAR T cell therapy, AntiMSLN chimeric antigen receptor T cell immunotherapy, TMMSTN01
Target
Action
inhibitors
Mechanism
MSLN inhibitors(Mesothelin inhibitors), Gene transference(Gene transference), T lymphocyte replacements
Originator Organization
Active Organization
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Triple Negative Breast CancerPhase 1
United States
06 Feb 2023
Pancreatic adenocarcinoma metastaticPhase 1
United States
15 Sep 2017
Adenocarcinoma of LungPhase 1
United States
06 Apr 2017
Fallopian Tube CarcinomaPhase 1
United States
06 Apr 2017
Malignant Mesothelioma of PeritoneumPhase 1
United States
06 Apr 2017
Mesothelin positive NeoplasmsPhase 1
United States
06 Apr 2017
Primary peritoneal carcinomaPhase 1
United States
06 Apr 2017
Recurrent ovarian cancerPhase 1
United States
06 Apr 2017
Ductus Arteriosus, PatentPhase 1
United States
01 Jul 2013
Metastatic Pancreatic CancerPhase 1
United States
01 Jul 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
65
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-
29 Apr 2025
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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