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Last update 05 Jul 2025
Anti-mesothelin CAR-T cell therapy (Tmunity Therapeutics/University of Pennsylvania)
Last update 05 Jul 2025
Overview
Basic Info
Drug Type CAR-T |
Synonyms AntiMSLN CAR T cell therapy, AntiMSLN chimeric antigen receptor T cell immunotherapy, TMMSTN01 |
Target |
Action inhibitors |
Mechanism MSLN inhibitors(Mesothelin inhibitors), Gene transference(Gene transference), T lymphocyte replacements |
Therapeutic Areas |
Active Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Related
6
Clinical Trials associated with Anti-mesothelin CAR-T cell therapy (Tmunity Therapeutics/University of Pennsylvania)NCT05623488
Phase 1, Adaptive-design Trial of Human Chimeric Antigen Receptor Modified T Cells in Patients With Mesothelin Expressing Breast Cancer
NCT05057715
Phase 1 Trial of Human Chimeric Antigen Receptor Modified T Cells (huCART-meso) Administered in Combination With VCN-01 in Patients With Pancreatic and Serous Epithelial Ovarian Cancer
NCT03323944
Phase I Study of Human Chimeric Antigen Receptor Modified T Cells (CAR T Cells) in Patients With Pancreatic Cancer
100 Clinical Results associated with Anti-mesothelin CAR-T cell therapy (Tmunity Therapeutics/University of Pennsylvania)
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100 Translational Medicine associated with Anti-mesothelin CAR-T cell therapy (Tmunity Therapeutics/University of Pennsylvania)
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100 Patents (Medical) associated with Anti-mesothelin CAR-T cell therapy (Tmunity Therapeutics/University of Pennsylvania)
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100 Deals associated with Anti-mesothelin CAR-T cell therapy (Tmunity Therapeutics/University of Pennsylvania)
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Triple Negative Breast Cancer | Phase 1 | United States | 06 Feb 2023 | |
| Pancreatic adenocarcinoma metastatic | Phase 1 | United States | 15 Sep 2017 | |
| Adenocarcinoma of Lung | Phase 1 | United States | 06 Apr 2017 | |
| Fallopian Tube Carcinoma | Phase 1 | United States | 06 Apr 2017 | |
| Malignant Mesothelioma of Peritoneum | Phase 1 | United States | 06 Apr 2017 | |
| Mesothelin positive Neoplasms | Phase 1 | United States | 06 Apr 2017 | |
| Primary peritoneal carcinoma | Phase 1 | United States | 06 Apr 2017 | |
| Recurrent ovarian cancer | Phase 1 | United States | 06 Apr 2017 | |
| Ductus Arteriosus, Patent | Phase 1 | United States | 01 Jul 2013 | |
| Metastatic Pancreatic Cancer | Phase 1 | United States | 01 Jul 2013 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
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Phase 1 | 65 | (Cohort 1) | imxfuvrwcu = fftvvekomf bsovunaiaq (gwyggapsmo, knuoobvdpr - gohtswzhri) View more | - | 29 Apr 2025 | ||
(Cohort 2) | imxfuvrwcu = dmvzxcpvch bsovunaiaq (gwyggapsmo, hyouugoxel - gmacxnbffc) View more |
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