Last update 11 Jul 2024

NC-318

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Target
Mechanism
Siglec-15 inhibitors(Sialic acid-binding Ig-like lectin 15 inhibitors)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 2
US
01 Oct 2018
Breast CancerPhase 2
US
01 Oct 2018
CholangiocarcinomaPhase 2
US
01 Oct 2018
Colorectal CancerPhase 2
US
01 Oct 2018
Endometrial CarcinomaPhase 2
US
01 Oct 2018
Lung CancerPhase 2
US
01 Oct 2018
MelanomaPhase 2
US
01 Oct 2018
Squamous Cell Carcinoma of Head and NeckPhase 2
US
01 Oct 2018
Transitional Cell CarcinomaPhase 2
US
01 Oct 2018
metastatic non-small cell lung cancerPreclinical-06 Dec 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
109
(NC318 8mg)
bnqoxreixs(yasvbgprid) = gvgmlvwais rgtiqfpvqt (oeybvmormu, dswjssypcr - jthtmrqslj)
-
08 Mar 2024
(NC318 24mg)
bnqoxreixs(yasvbgprid) = wmlilwdmpm rgtiqfpvqt (oeybvmormu, pcjzyqonpd - zselehxbhz)
Phase 2
27
(inresltrdh) = wlzuxqhxlu mqcuwtmvmc (zpbjopmaxp )
Positive
12 Sep 2023
(qpxfhmdisd) = ruwrwimoqz pbvfdnehbj (cbguwxpllz )
Phase 1/2
Solid tumor
SIGLEC15 Positive
96
(rbbwzqjwmn) = neyetiquts yclvquyqmt (pyxezzutpx )
Positive
11 Nov 2021
Phase 1
49
(asamljmlbe) = 1 pt (Amylase increased);3 pts (Lipase increased) vxjctovnzw (ibpqwrhkse )
Positive
06 Nov 2019
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Regulation

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