Drug Type Small molecule drug |
Synonyms 2-Mercapto-6-propyl-4-pyrimidone, 2-Mercapto-6-propylpyrimid-4-one, 2-Thio-4-oxo-6-propyl-1,3-pyrimidine + [16] |
Target |
Mechanism TPO inhibitors(Thyroid peroxidase inhibitors) |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date CA (31 Dec 1945), |
Regulation- |
Molecular FormulaC7H10N2OS |
InChIKeyKNAHARQHSZJURB-UHFFFAOYSA-N |
CAS Registry51-52-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00562 | Propylthiouracil |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Graves Disease | US | 28 Jul 1947 | |
Graves Disease | US | ENDO Medical, Inc.Startup | 28 Jul 1947 |
Graves Disease | US | 28 Jul 1947 | |
Toxic multinodular goiter | US | 28 Jul 1947 | |
Toxic multinodular goiter | US | ENDO Medical, Inc.Startup | 28 Jul 1947 |
Toxic multinodular goiter | US | 28 Jul 1947 | |
Hyperthyroidism | CA | 31 Dec 1945 |
Not Applicable | - | Propylthiouracil (PTU) | rtpcheffxa(bzpaqcbygx) = xdnpghhnhp vqeanpqiwc (ludeiutxen ) | Positive | 15 Nov 2016 | ||
Pulse dose steroids, plasma exchange, and immunotherapy | rtpcheffxa(bzpaqcbygx) = dspzohypai vqeanpqiwc (ludeiutxen ) |