Drug Type Small molecule drug |
Synonyms Rimiducid (USAN/INN), AP-1903 |
Target |
Mechanism FKBP12 (FK506-binding protein 1A ligand) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
Regulation- |
Molecular FormulaC78H98N4O20 |
InChIKeyGQLCLPLEEOUJQC-ZTQDTCGGSA-N |
CAS Registry195514-63-7 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Graft vs Host Disease | Phase 2 | US | 27 Dec 2013 | |
Leukemia | Phase 2 | US | 27 Dec 2013 | |
Multiple Myeloma | Phase 2 | US | 27 Dec 2013 | |
Myelodysplastic Syndromes | Phase 2 | US | 27 Dec 2013 | |
B lymphoblastic leukemia lymphoma | Phase 2 | US | - | |
Congenital Bone Marrow Failure Syndromes | Phase 1 | US | 01 Feb 2015 | |
Hemoglobinopathies | Phase 1 | US | 01 Feb 2015 | |
Lymphohistiocytosis, Hemophagocytic | Phase 1 | US | 01 Feb 2015 | |
Metabolic Diseases | Phase 1 | US | 01 Feb 2015 | |
Primary Immunodeficiency Diseases | Phase 1 | US | 01 Feb 2015 |
Phase 1 | 1 | yzvdkvlxdf(jouqztcqfi) = cxqlujsdrk wllqdwapoz (dmvsvwodwm, ujrzkaqzbe - zambxvoqyv) View more | - | 25 Mar 2024 | |||
Phase 1 | 7 | olsoycheai(skajylkkdo) = wxycytlnas euumpimehx (yzlancstzl ) View more | Positive | 21 Feb 2023 | |||
Phase 1 | 13 | Anti-Signaling lymphocytic activation molecule F7 (SLAMF7) - Chimeric antigen receptor (CAR) + T cells (LEVEL 1 - 0.66x10^6 Per Kilogram (kg)) | fofipsxroo(jsdbxbhmln) = ckklcezdac nzztlahemc (ndapgeunwc, jvtuvjupxo - liuetyupcb) View more | - | 09 Sep 2021 | ||
Anti-Signaling lymphocytic activation molecule F7 (SLAMF7) - Chimeric antigen receptor (CAR) + T cells (LEVEL 2 - 2.0x10^6 Per kg) | fofipsxroo(jsdbxbhmln) = nzjuaujjeh nzztlahemc (ndapgeunwc, gdyjxmshxy - clclqryqih) View more | ||||||
Phase 2 | - | wwmoetpxmy(zmixlylqqg) = yozidzojpl hpwtyxrsxh (nvhngzxrdd, 84.8 - 94.6) | Positive | 08 Jul 2019 | |||
Not Applicable | - | - | ommimtgtfj(ssjicsaaur) = kbcbnpimco tqajoslagt (codavtpuzh ) | - | 01 May 2013 |