Drug Type Small molecule drug |
Synonyms Cinaciguat (JAN/INN), BAY-582667 |
Target |
Action stimulants |
Mechanism sGC stimulants(Soluble guanylate cyclase stimulants) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC36H39NO5 |
InChIKeyWPYWMXNXEZFMAK-UHFFFAOYSA-N |
CAS Registry329773-35-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D07577 | Cinaciguat | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Decompensated chronic heart failure | Phase 2 | United States | 01 Dec 2007 | |
Decompensated chronic heart failure | Phase 2 | Canada | 01 Dec 2007 | |
Decompensated chronic heart failure | Phase 2 | Croatia | 01 Dec 2007 | |
Decompensated chronic heart failure | Phase 2 | Czechia | 01 Dec 2007 | |
Decompensated chronic heart failure | Phase 2 | Estonia | 01 Dec 2007 | |
Decompensated chronic heart failure | Phase 2 | Germany | 01 Dec 2007 | |
Decompensated chronic heart failure | Phase 2 | Hungary | 01 Dec 2007 | |
Decompensated chronic heart failure | Phase 2 | Israel | 01 Dec 2007 | |
Decompensated chronic heart failure | Phase 2 | Italy | 01 Dec 2007 | |
Decompensated chronic heart failure | Phase 2 | Lithuania | 01 Dec 2007 |
Phase 2 | 139 | lqwqvwjwor(xqbntsxaky) = the trial was stopped prematurely due to an increased occurrence of hypotension at cinaciguat doses ≥200 µg/h ridevrvzos (pqejpzsscg ) | - | 01 Jan 2013 | |||
Placebo | |||||||
Not Applicable | - | (Diabetic control) | zpcpzybysn(dsmoohwtqk) = geuzfwncdc jqvvxyfhdq (ostdkgwqfh ) | - | 01 May 2012 | ||
Diabetic + Cinaciguat treatment | zpcpzybysn(dsmoohwtqk) = hiuybhchys jqvvxyfhdq (ostdkgwqfh ) |