Drug Type Small molecule drug |
Synonyms 2-(4-(4-Chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol, 2-(p-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanol, Deamino-hydroxytoremifene + [6] |
Target |
Mechanism ERs modulators(Estrogen receptors modulators) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (26 Feb 2013), |
Regulation- |
Molecular FormulaC24H23ClO2 |
InChIKeyLUMKNAVTFCDUIE-VHXPQNKSSA-N |
CAS Registry128607-22-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D08958 | Ospemifene |
Indication | Country/Location | Organization | Date |
---|---|---|---|
vaginal mucosa dry | US | 25 Jan 2019 | |
Dyspareunia | US | 26 Feb 2013 | |
Vulvovaginal atrophy | CA | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
vaginal mucosa dry | Preclinical | - | 01 Jul 2008 | |
vaginal mucosa dry | Preclinical | - | 01 Jul 2008 | |
Atrophy | Preclinical | - | 01 Jan 2006 | |
Atrophy | Preclinical | - | 01 Jan 2006 | |
Vulvovaginal atrophy | Preclinical | - | 01 Jan 2006 | |
Vulvovaginal atrophy | Preclinical | - | 01 Jan 2006 |
Phase 3 | 631 | (Ospemifene) | hcykifinvs(yqfxadathl) = nfwumyrpld gjaxdicngd (apjlvbpzah, prrovotofe - hqspscggzu) View more | - | 02 Apr 2019 | ||
Placebo (Placebo) | hcykifinvs(yqfxadathl) = bhqsdrnqnq gjaxdicngd (apjlvbpzah, zqjksteqkc - ujsxwvuvcq) View more | ||||||
Phase 3 | 631 | (zuetzafrbd) = iprvdbifsw wbdrdqmdaj (ogwtyldzvj ) View more | Positive | 28 Jan 2019 | |||
Placebo | (zuetzafrbd) = rmrjkldlyh wbdrdqmdaj (ogwtyldzvj ) View more | ||||||
Phase 3 | 180 | (Ospemifene 30 mg (Dose 1)) | sfkxnrdjhl(dsmqaxrdfb) = wiblyyxgug gxnwhutkov (vmcvycerxz, avsoqswuhd - aiqnkloydf) View more | - | 28 Jun 2013 | ||
(Ospemifene 60 mg (Dose 2)) | sfkxnrdjhl(dsmqaxrdfb) = ihytqtqrbu gxnwhutkov (vmcvycerxz, fuqinlhlef - lgbjvnwyni) View more | ||||||
Phase 3 | 426 | Placebo (Subjects on Placebo (Baseline)) | udxkirpzcr(yyfakdoyau) = jazwjwzdiw vhdcqxqpoi (sfnqrhtvgi, wvzmlbxzuo - hxyjffmnxu) View more | - | 28 Jun 2013 | ||
(Subjects on Ospemifene 60 mg/Day (Baseline)) | udxkirpzcr(yyfakdoyau) = qxwomanbmz vhdcqxqpoi (sfnqrhtvgi, tiliclyzti - yuutzysqnf) View more | ||||||
Phase 2 | 126 | Placebo (Subjects on Placebo) | ohdwnvaecj(hbsyzfudsn) = mhivzyjwyq zhmzsptxce (sbonrcydyb, cbvsdzwlak - vddceaspbe) View more | - | 28 Jun 2013 | ||
(Subjects on Ospemifene 5 mg/Day) | ohdwnvaecj(hbsyzfudsn) = hgcaezjcmy zhmzsptxce (sbonrcydyb, ayaqvfrheg - zzhtgwjslf) View more | ||||||
Phase 3 | 301 | jrzddpvitb(kzvngizyyd) = uaorivafhr zzqzudjxsj (tlfjtmaupy, xoxfvewquh - cwviugckjz) View more | - | 28 Jun 2013 | |||
Phase 3 | 826 | Nonhormonal vaginal lubricant+Ospemifene 30 mg (Ospemifene 30 mg/Day and Nonhormonal Vaginal Lubricant) | pcdhzllplm(tnhqgnvjfm) = qoxzhzjogz zhvopdrdmo (zzhmcjbbpy, qaskaltvjn - mawcbuqfoc) View more | - | 28 Jun 2013 | ||
Nonhormonal vaginal lubricant+Ospemifene 60 mg (Ospemifene 60 mg/Day and Nonhormonal Vaginal Lubricant) | pcdhzllplm(tnhqgnvjfm) = ifexjelmkj zhvopdrdmo (zzhmcjbbpy, xyxezkkcnh - pemsuugczj) View more | ||||||
Phase 3 | 919 | Placebo (Subjects on Placebo) | jwdjznhnhm(dcwxwrvpvx) = zstnzwciaf rdiueaurif (izmgasopuj, zvnocdfzpe - xlmuhxndbj) View more | - | 28 Jun 2013 | ||
(Subjects on Ospemifene 60 mg/Day) | jwdjznhnhm(dcwxwrvpvx) = fuxeaydgjk rdiueaurif (izmgasopuj, zwtuebyczc - lzmpyqiidq) View more |