Last update 11 Jul 2024

Bifikafusp alfa

Overview

Basic Info

Drug Type
Antibody fusion proteins
Synonyms
Anti-EDB-IL2 antibody conjugate, Anti-EDB-interleukin-2 antibody conjugate, Darleukin
+ [4]
Mechanism
EDB-FN inhibitors(Human fibronectin extra domain B inhibitors), IL-2R agonists(Interleukin-2 receptor agonists)
Originator Organization
Active Organization
Drug Highest PhasePhase 3
First Approval Date-
Regulation-

R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
MelanomaPhase 3--
Pancreatic CancerPhase 3
DE
-
Pancreatic CancerPhase 3
IT
-
Diffuse Large B-Cell LymphomaPhase 2--
Diffuse Large B-Cell LymphomaPhase 2--
Pancreatic CancerPhase 2--
Pancreatic CancerPhase 2--
Advanced Malignant Solid NeoplasmPreclinical
DE
01 Nov 2005
Advanced Malignant Solid NeoplasmPreclinical
IT
01 Nov 2005
Renal Cell CarcinomaDiscovery
EU
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
20
(usokajogrs) = 32 melanoma lesions;53.8% non-injected lesions (4 cutaneous, 3 lymph nodes) lvtcvxcecv (psxownoang )
Positive
01 Aug 2015
Phase 2
29
gqqrekeyws(jwvmeduqcl) = qzntjuooif nsyvgzucbp (ncswfdgtqx )
Positive
15 Dec 2011
Not Applicable
32
(jqcsaxkzgp) = avjkevbyak owuqnqwwmx (ntbarvwcpu )
Positive
20 May 2011
Phase 1/2
10
quzlskewdh(bkmjjjtvgr) = psaqhiecgt wggmzaljzs (xdbxdbktwo )
-
20 May 2009
Phase 1/2
33
(qelvevlbhb) = wzcsufjklo uqitzaeanh (ycopdxygtu )
-
20 May 2008
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Regulation

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