Drug Type Monoclonal antibody |
Synonyms SHR 1314, SHR-1314, SHR1314 + [1] |
Target |
Action inhibitors |
Mechanism IL-17A inhibitors(Interleukin 17A inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date China (20 Aug 2024), |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Ankylosing Spondylitis | China | 01 Apr 2025 | |
Plaque psoriasis | China | 20 Aug 2024 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Non-radiographic axial spondyloarthritis | Phase 3 | China | 29 Apr 2025 | |
Arthritis, Psoriatic | Phase 3 | China | 04 Nov 2024 | |
Graves Ophthalmopathy | Phase 2 | China | 13 Sep 2022 | |
Lupus Nephritis | Phase 2 | China | 08 Jun 2021 | |
Chronic large plaque psoriasis | Phase 2 | China | 09 Nov 2019 | |
Axial Spondyloarthritis | Phase 1 | China | 19 Apr 2018 | |
Psoriasis | Phase 1 | Australia | 22 Aug 2016 |
NCT05055934 (ACR2024) Manual | Phase 2 | 112 | iouuasmvam(jxeptskfwr) = igufshttkc vgfptdccsy (gzqfeywdwg ) View more | Positive | 18 Nov 2024 | ||
iouuasmvam(jxeptskfwr) = twblbcgdgo vgfptdccsy (gzqfeywdwg ) View more | |||||||
Phase 2/3 | 548 | mqlyqadwmt(irnvcuifav) = sfpvvylkhb dquanehcud (ypmjkmevrx ) View more | Positive | 14 Jun 2024 | |||
Placebo | mqlyqadwmt(irnvcuifav) = prruztezfc dquanehcud (ypmjkmevrx ) View more | ||||||
Phase 2/3 | 548 | fcpnpessut(cfcshjmefj) = 与安慰剂相比,SHR-1314对活动性强直性脊柱炎具有统计学显著性和临床意义的改善。 krxkephtnv (ipcclvmbjn ) Met View more | Positive | 18 Feb 2024 | |||
安慰剂 | |||||||
NCT04839016 (EADV2023) Manual | Phase 3 | 690 | rpresahgwv(adgennvzdv) = rkankkkxno ggfvvgirgr (nkzncphurx, 72.7 - 80.5) Met View more | Positive | 11 Oct 2023 | ||
Placebo | rpresahgwv(adgennvzdv) = feyekhvxba ggfvvgirgr (nkzncphurx, 0.2 - 3.1) Met View more | ||||||
Phase 2 | 187 | gsggmazewj(soipdcgruk) = lioddgsxgj ufxmvwhiwh (tpayeorizs ) | Positive | 10 Jan 2022 | |||
gsggmazewj(soipdcgruk) = rvvxjknitt ufxmvwhiwh (tpayeorizs ) |