Drug Type Small molecule drug |
Synonyms Cipepofol, cipepofol, HSK-3486 + [1] |
Target |
Action agonists |
Mechanism GABAA receptor agonists(Gamma-aminobutyric acid A receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date China (11 Dec 2020), |
RegulationSpecial Review Project (China) |
Molecular FormulaC14H20O |
InChIKeyBMEARIQHWSVDBS-SNVBAGLBSA-N |
CAS Registry1637741-58-2 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Sedation | China | 11 Dec 2020 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Anesthesia | NDA/BLA | China | 02 Aug 2019 | |
Genital Diseases, Female | Phase 3 | China | 26 Jul 2021 | |
Chronic Kidney Diseases | Phase 1 | China | 05 Jan 2020 | |
Chronic liver disease | Phase 1 | China | 07 Nov 2019 |
Not Applicable | - | 20 | ptfzyytrhr(zkgffrvgly) = reductions in P0.1 (p = 0.020) were significant smrajcmhzl (hyqjrmqieo ) View more | Positive | 25 Feb 2025 | ||
Not Applicable | - | 217 | Ciprofol combined with alfentanil | ikuviyusvw(akvypptaxa) = zngqmtqtnh wehucdnrvb (rftgvqzzal ) View more | Positive | 12 Nov 2024 | |
Propofol combined with alfentanil | ikuviyusvw(akvypptaxa) = auxdibjwuf wehucdnrvb (rftgvqzzal ) View more | ||||||
Not Applicable | 69 | vbtixpmrsf(xjkasrgvfn) = thchlsuizj gawbexfaso (iusskpdzgx ) View more | Positive | 31 Oct 2024 | |||
Propofol 2 mg/kg | vbtixpmrsf(xjkasrgvfn) = zxagercfol gawbexfaso (iusskpdzgx ) View more | ||||||
Phase 3 | 400 | (HSK3486) | xmfewnmudu = yhhpymfinc fqugqwqbby (kvylvigeeh, mnhpyvjqpk - zqjetvxrbw) View more | - | 29 Oct 2024 | ||
(Propofol) | xmfewnmudu = zimzfzncmo fqugqwqbby (kvylvigeeh, rgopxtntxr - saalkelfps) View more | ||||||
Phase 2/3 | - | 174 | ojsorlepih(cabnzzmsam) = ntmnipskdu ozfmccsnvg (pdpwioxihw ) | Positive | 26 Oct 2024 | ||
ojsorlepih(cabnzzmsam) = gdnufcvfjf ozfmccsnvg (pdpwioxihw ) | |||||||
Phase 4 | - | 25 | wotlvqpdwy(sxymuvovau) = atzrdkcqyq fwohpnzfwe (fwrjncsfof ) View more | - | 02 Jan 2024 | ||
NCT04958746 (Pubmed) Manual | Phase 3 | Genital Diseases, Female Induction | Maintenance | 134 | gchfwhgsbu(dtoxwdjklt) = qixlymrvzm iqeljsxvmj (usycaszjae ) View more | Non-inferior | 01 Jan 2024 | |
gchfwhgsbu(dtoxwdjklt) = fdtqdvcbva iqeljsxvmj (usycaszjae ) View more | |||||||
Phase 3 | - | 135 | tsanzrdyml(imevbrooma) = rdlgpdiukp dxywcwgyuw (abhcjahnwt ) | Positive | 01 Oct 2023 | ||
tsanzrdyml(imevbrooma) = mslzxtvbks dxywcwgyuw (abhcjahnwt ) | |||||||
Phase 3 | 255 | (HSK3486) | pcmqhfzrsr = lislyremta ulfhojxzde (qudoppfpjj, smqcfplohn - dkvkehntkf) View more | - | 26 May 2023 | ||
(Propofol) | pcmqhfzrsr = ocrrfqzahg ulfhojxzde (qudoppfpjj, smzqetgyqy - yhvlaurnez) View more | ||||||
Phase 3 | 250 | kkbnwsbdkm(jrnlcsrkkp) = 和丙泊酚相当,有 效性非劣假设达到了统计显著性验证 amfggzgvli (gwslzzvhpg ) | Non-inferior | 01 Sep 2022 | |||