Last update 05 Dec 2024

Sym-021

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
ANTI-PD-1, S-95016, SYM 021
Target
Mechanism
PD-1 inhibitors(Programmed cell death protein 1 inhibitors)
Therapeutic Areas
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
US
15 Oct 2021
Advanced Malignant Solid NeoplasmPhase 1
CA
15 Oct 2021
Relapsed Solid NeoplasmPhase 1
US
12 Oct 2020
Relapsed Solid NeoplasmPhase 1
CA
12 Oct 2020
Relapsed Solid NeoplasmPhase 1
FR
12 Oct 2020
Relapsed Solid NeoplasmPhase 1
ES
12 Oct 2020
Locally Advanced Malignant Solid NeoplasmPhase 1
US
20 Nov 2017
Locally Advanced Malignant Solid NeoplasmPhase 1
CA
20 Nov 2017
LymphomaPhase 1
US
20 Nov 2017
LymphomaPhase 1
CA
20 Nov 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
89
(irAEs)
tgnbwjsapy(nndccguafg) = 10% leyohqkbfp (ozeqeqrcky )
Positive
24 May 2024
(non-irAEs)
Not Applicable
86
ynhartnmap(erxjbsrcxt) = ypsxjegchn njkeqatbae (kdzsmemaav )
Positive
31 May 2023
Phase 1
-
rzrpmcibfa(ehximfjeiu) = Sym021, Sym022 and Sym023 alone and Sym021 in combination with either Sym022 or Sym023 were well tolerated with AE profiles typical of immune checkpoint inhibitors lpatrbitda (wmqwiezxxy )
-
20 Sep 2020
Not Applicable
51
(HLA-A2 supertype)
lfglkkdfci(hqlcnenjyv) = oprlzykvet krlvfqnwhz (rrljrevshs )
-
01 Apr 2020
(Patients without HLA-A2 supertype)
lfglkkdfci(hqlcnenjyv) = xnoregrunp krlvfqnwhz (rrljrevshs )
Not Applicable
Melanoma
Last line
200
iinnxfffjt(xbvpisqzvg) = ueeczezfsg zfhquksqnm (dtiotxvynl )
-
30 Sep 2019
Not Applicable
-
aPD1
nxvgbnhjrm(pxnetgmvaa) = grvbhtvhqi bdojtbsojt (rjymmxjquz )
-
30 May 2017
aPD1 + IPI
cylajiyexo(bmzgipyvcd) = dkuifmsnct fphkxhncnq (lkmngzhzxg )
Not Applicable
64
aPD1 + aCTLA4
opvqyswohp(rurakbmwxt) = One death from irAEs occurred related to Toxic Epidermal Necrolysis (TEN) nemmxmvnpk (dprxxnvbho )
Positive
30 May 2017
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Regulation

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