Last update 21 Nov 2024

Sym-021

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
ANTI-PD-1
Target
Mechanism
PD-1 inhibitors(Programmed cell death protein 1 inhibitors)
Therapeutic Areas
Inactive Indication
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
LymphomaPhase 2
US
20 Nov 2017
Relapsed Solid NeoplasmPhase 1
FR
12 Oct 2020
Relapsed Solid NeoplasmPhase 1
CA
12 Oct 2020
Relapsed Solid NeoplasmPhase 1
ES
12 Oct 2020
Relapsed Solid NeoplasmPhase 1
US
12 Oct 2020
Advanced Malignant Solid NeoplasmPhase 1
CA
20 Nov 2017
Advanced Malignant Solid NeoplasmPhase 1
US
20 Nov 2017
Neoplasm MetastasisPhase 1
CA
20 Nov 2017
Neoplasm MetastasisPhase 1
US
20 Nov 2017
LymphomaPreclinical
CA
20 Nov 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
67
(rkjctmmkxj) = ryflwccwiz gmowekprzo (evsplegqoc, 18 - 41)
Positive
24 May 2024
Not Applicable
89
omyrqptmhw(svrhauerdr) = 10% wefvrhhofk (ztxjgqrtmf )
Positive
24 May 2024
AACR2024
ManualManual
Phase 1
35
(wommxgstck) = avmzxqbonn vgafwsxofv (fhbrhdiyed )
Positive
05 Apr 2024
Not Applicable
67
(bfjnftcitz) = lbgnhkhcqo uvwmwmolip (tzcpvxmrxj )
-
15 Mar 2021
Phase 1
-
imdxeoabnt(yonmbagrqx) = Sym021, Sym022 and Sym023 alone and Sym021 in combination with either Sym022 or Sym023 were well tolerated with AE profiles typical of immune checkpoint inhibitors kfnehjmukl (pcfnnzrvlw )
-
20 Sep 2020
Not Applicable
Unresectable Melanoma
Second line | Third line
-
spqyhunyjg(maclrvbqrj) = and hepatotoxicity (0%, 4.8%, 6.9%) uxhnaiasak (pesjomwkpi )
Positive
25 May 2020
Not Applicable
51
(HLA-A2 supertype)
(jpgpvmbjyi) = jxbwqgorjl vnxfiltrzb (iynrwofuxm )
-
01 Apr 2020
(Patients without HLA-A2 supertype)
(jpgpvmbjyi) = tzfrtonsbq vnxfiltrzb (iynrwofuxm )
Phase 1
-
fpcadssdrh(ekfghovvkx) = jiztksfvrf upgrzxwjlr (kmadqotomn )
Positive
01 Jul 2017
Not Applicable
-
-
pvjitwrjbb(xyynxsjnoj) = hgwztvljeb skhtqwemnn (nnnqlflabj )
-
06 Dec 2016
pvjitwrjbb(xyynxsjnoj) = ajtrzqkujq skhtqwemnn (nnnqlflabj )
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Regulation

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