Request Demo

Last update 20 Mar 2025

Resorcinol

Last update 20 Mar 2025

Overview

R&D Status

Clinical Result

Translational Medicine

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

1,3-Benzenediol, 1,3-Dihydroxybenzene, Resorcin (JAN)

+ [4]

Target-

Action-

Mechanism-

Therapeutic Areas

Skin and Musculoskeletal Diseases

Active Indication

Alopecia AreataDermatitis, Seborrheic

Inactive Indication-

Originator Organization-

Active Organization-

Inactive Organization-

Drug Highest PhaseApproved

First Approval Date-

Regulation-

Structure/Sequence

Molecular FormulaC6H6O2

InChIKeyGHMLBKRAJCXXBS-UHFFFAOYSA-N

CAS Registry108-46-3

100 Clinical Results associated with Resorcinol

100 Translational Medicine associated with Resorcinol

100 Patents (Medical) associated with Resorcinol

24,868

Literatures (Medical) associated with Resorcinol

01 Jul 2025·Separation and Purification Technology

Resorcin[4]arene-derived hierarchical porous organic polymer modulated polyamide TFC membrane for effective ion separation

Author: Sun, Qianlong ; Xia, Chao ; Meng, Jianqiang ; Yuan, Bingbing ; You, Meng

Fine-customized structure and morphol. of the thin-film-composite polyamide membranes (TFC-PA) play an essential role in obtaining high water permeance and solute-solute selectivity.Herein we fabricated a TFC-PA nanofiltration membrane with excellent separation performance by the regulation of the interfacial polymerization process via a resorcin[4]arene-derived hierarchical POPs intermediate layer (RA-POPs).The RA-POPs interlayer was constructed on the PSF substrate surface through in situ covalent assembly by the azo-coupling reaction, followed by the formation of the PA layer on top of this porous layer.The effect of azo-coupling reaction conditions on the morphologies and performance of the prepared TFC-PA-POPs membranes was investigated.The constructed RA-POPs layer interlayer increased the hydrophilicity of the substrates.This hydrophilic RA-POPs interlayer facilitated the uniform distribution of the amine solution and slowed down the PIP diffusion into the organic phase by the supramol. interactions.Consequently, the formed PA layer exhibited a thinner thickness, a high degree of crosslinking, a crumpled structure and an enhanced neg. charged surface.The obtained TFC-PA-POPs membranes possessed high water permeance of 21.0 L m^-2 h^-1 bar^-1, comparable Na₂SO₄ rejection of 99.35 % and excellent mixed ion selectivity (Cl^-/SO^2-₄) of 340 in the high salt concentration, which is superior to the com. and the state-of-the-art polyamide-based NF membranes.The reduced pore size, narrowed pore size distribution and enhanced surface neg. charge endowed the TFC-PA-POPs membranes with high mono/multivalent anions selectivity.Our approach for modulating the polyamide microstructure by incorporating macrocycle-derived hierarchical porous organic polymer interlayer has provided insight into the design of TFC-PA NF membranes with high water permeance and precise ion separation for high-salinity wastewater treatment and water purification

01 Jun 2025·Separation and Purification Technology

Boosting photocatalytic H2O2 production by incorporating extra electron-donor group over resorcinol-formaldehyde resin

Author: Wu, Yongsheng ; Che, Chunyu ; Wang, Wenjing ; Zhang, Chuanqi ; Chu, Hongxiang ; Jia, Taikang ; Li, Ruofan ; Qin, Xin ; Wang, Wenzhong ; Zhang, Ling ; Jiang, Bei ; Xu, Shenyan

The photocatalytic production of hydrogen peroxide from water and oxygen using solar energy presents a promising approach.Nevertheless, challenges persist regarding the efficiency of this process and the clarification of the underlying catalytic mechanisms.In this study, we synthesized a donor-acceptor type photocatalyst, modified resorcinol-formaldehyde resin.FT-IR and XPS analyses confirmed the successful incorporation of an addnl. electron donor unit, N, N-dimethylaniline, which interacts with the electron acceptor unit to facilitate the directed migration of photogenerated electrons.Furthermore, this modification creates an electron-rich carbonyl active center, enhancing its capacity to adsorb and reduce O2, thereby improving the photocatalytic production of H2O2.In situ EPR and DRIFT analyses identified key intermediates, substantiating a two-step, single-electron oxygen reduction pathway and providing insights into the catalytic mechanism.Importantly, without the use of sacrificial agents or addnl. aeration, the photocatalytic production rate of H2O2 reached 22.8 μmol.h-1, underscoring its potential as an effective photocatalyst.This study elucidates the reaction mechanism during the photocatalytic process, offering valuable insights for future material design aimed at enhancing hydrogen peroxide production rates.

01 Jun 2025·Separation and Purification Technology

Ultra-fast interlayer construction strategy for the preparation of NF membranes with high Li+/Mg2+ separation performance

Author: Bai, Shibo ; Li, Mengxin ; Liu, Xinliang ; Wang, Ming ; Hou, Yingfei ; Miao, Chuanyu ; Jiang, Chi ; Li, Jiawang

In this paper, NF membranes with high permeate flux and high lithium-magnesium separation factor (SLi,Mg) were prepared by using a polyamide (PA) layer as the separation layer, RA-PEI as the interlayer, and a polysulfone (PSf) membrane as the substrate membrane.Notably, the RA-PEI co-deposition modification method is an ultra-fast substrate modification method, requiring only 1s for modifying PSf substrates.At the same time, RA-PEI firmly adheres to the surface of the PSf substrate by the synergistic effects of intermol. hydrogen bonding interactions and π-π interactions.This was further verified by comparing the adsorption energies of different kinds of organic interlayers and PSf substrates obtained from mol. dynamics (MD) simulations.Correlation characterization showed that the RA-PEI interlayer endowed the NF membranes with reduced average pore size as well as attenuated electronegativity, thus realizing the efficient separation of Mg2+ and Li+.The performance assessment showed that the membrane containing RA-PEI interlayer exhibited excellent separation performance and permeate flux in simulated salt-lake brine (2000 ppm, WMg/Li=20), where SLi,Mg (92.8) and permeate flux (16.7 L.m-2.h-1.bar-1) were improved by 7.8 and 2.2 times, resp., in comparison to the pristine NF membrane.Therefore, this work provides a useful contribution to the practical use of NF membranes for lithium extraction from salt lakes.

100 Deals associated with Resorcinol

External Link

KEGG	Wiki	ATC	Drug Bank
D00133	-	-	DB11085

R&D Status

10 top approved records.

to view more data

Indication	Country/Location	Organization	Date
Alopecia Areata	China	-	-
Dermatitis, Seborrheic	China	-	-

Clinical Result

Indication

Phase

Evaluation

View All Results

Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


EADV2022 Manual	Phase 1	Hidradenitis Suppurativa	60	10% resorcinol	(ibzplmjwyc) = Treatment with resorcinol 10% resulted in asignificant reduction in mean total lesion countat 4, 12 and 24 weeks of resorcinol application. lorcemscyf (ntzjdihkcx ) View more	Positive	07 Sep 2022
				clindamycin lotion 1%

Translational Medicine

Boost your research with our translational medicine data.

view full example data

Deal

Boost your decision using our deal data.

view full example data

Core Patent

Boost your research with our Core Patent data.

view full example data

Clinical Trial

Identify the latest clinical trials across global registries.

view full example data

Approval

Accelerate your research with the latest regulatory approval information.

view full example data

Regulation

Understand key drug designations in just a few clicks with Synapse.

view full example data

Chat with Hiro

Get started for free today!

Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.

Start your data trial now!

Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.

Bio

Bio Sequences Search & Analysis

Chemical

Chemical Structures Search & Analysis

Resorcinol

Overview

Basic Info

Structure/Sequence

Related

External Link

R&D Status

Clinical Result

Translational Medicine

Deal

Core Patent

Clinical Trial

Approval

Regulation