Drug Type Small molecule drug |
Synonyms Adenazole, Tocladesine (USAN/INN), 8-CL-CAMP + [4] |
Target |
Mechanism caspase 3 inhibitors(Caspase-3 inhibitors), Cyclic AMP agonists |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC10H11ClN5O6P |
InChIKeyCLLFEJLEDNXZNR-UUOKFMHZSA-N |
CAS Registry41941-56-4 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Plasma cell myeloma refractory | Phase 2 | US | 01 Jan 1998 | |
Relapse multiple myeloma | Phase 2 | US | 01 Jan 1998 | |
Colorectal Cancer | Phase 2 | US | - | - |
Colorectal Cancer | Phase 2 | - | - | |
Colorectal Cancer | Phase 2 | - | - | |
Metastatic Colorectal Carcinoma | Phase 1 | US | 01 Apr 2001 | |
Neoplasms | Phase 1 | JP | - | - |
Neoplasms | Phase 1 | IT | - | - |
Neoplasms | Phase 1 | GB | - | - |