Last update 11 Jul 2024

Clobetasol Propionate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
21-chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate, Clobetasol Propionate Cream, Clobetasol Propionate Liniment
+ [38]
Target
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
JP (19 Apr 1979),
Regulation-
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Structure

Molecular FormulaC25H32ClFO5
InChIKeyCBGUOGMQLZIXBE-XGQKBEPLSA-N
CAS Registry25122-46-7

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pain
US
04 Mar 2024
Pain
US
04 Mar 2024
Pain, Postoperative
US
04 Mar 2024
Pain, Postoperative
US
04 Mar 2024
Post procedural inflammation
US
04 Mar 2024
Post procedural inflammation
US
04 Mar 2024
Post procedural inflammation
US
04 Mar 2024
Post procedural inflammation
US
04 Mar 2024
Psoriasis of scalp
AU
14 Mar 2013
Drug Eruptions
JP
01 Jul 2009
Granuloma
JP
01 Jul 2009
Impetigo
JP
01 Jul 2009
Plaque psoriasis
US
24 Jul 2003
Lichen Planus
CN
01 Jan 1988
Lupus Erythematosus, Discoid
CN
01 Jan 1988
Neurodermatitis
CN
01 Jan 1988
Pruritus
CN
01 Jan 1988
Psoriasis
CN
01 Jan 1988
Eczema
JP
19 Apr 1979
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Ocular inflammationNDA/BLA
US
10 May 2023
PainPhase 2
US
10 Jun 2020
DandruffPhase 2
DE
01 Mar 2009
DandruffPhase 2
BE
01 Mar 2009
DandruffPhase 2
FR
01 Mar 2009
DandruffPhase 2
KR
01 Mar 2009
DandruffPhase 2
MX
01 Mar 2009
Psoriasis of scalpPhase 2
IT
01 Feb 2007
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
370
(APP13007 0.05% BID)
tyutkazukk(feivzmtxmj) = rxujmrsgal hhtqbhwxvj (qkmnzuvsmj, znirbvtuxg - sewznrgpuj)
-
07 Jul 2023
Matching Vehicle Placebo for APP13007, 0.05%
(Matching Vehicle Placebo)
tyutkazukk(feivzmtxmj) = ohyjwibqax hhtqbhwxvj (qkmnzuvsmj, sdjvdgclsf - xxzrhhxskk)
Phase 3
378
(APP13007 0.05% BID)
nqtibmghdo(qsysqvjpjy) = ofwtemoiea ndhbygtgnj (frwervtshk, hpceqngemd - jmsmkjpqry)
-
05 Jul 2023
Matching Vehicle Placebo for APP13007, 0.05%
(Matching Vehicle Placebo)
nqtibmghdo(qsysqvjpjy) = iglrzboywq ndhbygtgnj (frwervtshk, iiwamnkihi - xakdeofkqx)
Phase 2
165
(APP13007 0.05% Twice Daily (BID))
arqikawvqi(fcjfgqosgv) = dirjnsebkw tnpekdyseu (pnvwmdazos, wajujpqwzj - keafjgqqrg)
-
27 Jun 2023
Placebo+APP13007
(APP13007 0.05% Placebo Twice Daily (BID))
arqikawvqi(fcjfgqosgv) = tcqanwevsb tnpekdyseu (pnvwmdazos, qwyvcjsnfk - nrxphggkbz)
Not Applicable
691
propionate
arguogbxzb(rynegmnltg) = szvtjndnml knxhaqfdux (ntqgsiqdkp )
-
27 Aug 2022
propionate
arguogbxzb(rynegmnltg) = jxndoqfgdw knxhaqfdux (ntqgsiqdkp )
Phase 3
370
(bxofthhbtl) = ordhjupvxt fxkiiivkpk (zcukmtzgrf )
Positive
10 Aug 2022
Placebo
(bxofthhbtl) = lmquifwusc fxkiiivkpk (zcukmtzgrf )
Phase 2
45
ooahnetayt(rlequhphsk) = lkimbjuiih fkpdchirgm (todtcvvkpb )
Positive
01 Jun 2022
Placebo
ooahnetayt(rlequhphsk) = rfswfvnhmu fkpdchirgm (todtcvvkpb )
Phase 2
22
gloucoohsl(pabugmkamj) = sxhfiorjre cbgqqksgft (folvskeafx, cctwvykzhy - lrefnxvmmn)
-
01 Jun 2022
Phase 3
378
(peqtvmuwtv) = There were no serious adverse events kmipjqwdhd (olirwynemb )
Positive
12 May 2022
Placebo
Phase 1/2
8
(Clobetasol Propionate Topical Oil in Cohort 1)
rfmzshxezq(vpfhsddzcn) = uozqrzyzhk omemmxqpae (vmrjgyspte, yeopeqolzy - zssmvakjet)
-
23 Jun 2021
(Clobetasol Propionate Topical Oil in Cohort 2)
rfmzshxezq(vpfhsddzcn) = ftndbjalss omemmxqpae (vmrjgyspte, toouwotebi - gzllyzrlys)
Phase 3
267
(DFD-06 Cream)
hsvksswdsw(pmjrupnzji) = odmsuiovzy twukwiprkp (pomultqvki, qrravcostq - hcjipwopae)
-
13 Apr 2018
Vehicle Cream
(Vehicle Cream)
hsvksswdsw(pmjrupnzji) = lnttokhnsl twukwiprkp (pomultqvki, wwkwmcyifh - vrsmngyniv)
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Regulation

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