Drug Type Radiolabeled antibody, Diagnostic radiopharmaceuticals |
Synonyms 89-Zr CD8 ImmunoPET minibody - ImaginAb Inc, 89Zr CD8 Immuno-PET agent - ImaginAb, [89Zr]Zr-Df-Crefmirlimab + [12] |
Target |
Action inhibitors |
Mechanism CD8A inhibitors(CD8a molecule inhibitors) |
Therapeutic Areas |
Active Indication |
Originator Organization |
Inactive Organization- |
License Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Locally Advanced Malignant Solid Neoplasm | Phase 2 | Netherlands | 11 Mar 2025 | |
Locally Advanced Malignant Solid Neoplasm | Phase 2 | Spain | 11 Mar 2025 | |
Locally Advanced Malignant Solid Neoplasm | Phase 2 | United Kingdom | 11 Mar 2025 | |
Merkel Cell Carcinoma | Phase 2 | United States | 09 Dec 2021 | |
Merkel Cell Carcinoma | Phase 2 | Australia | 09 Dec 2021 | |
Merkel Cell Carcinoma | Phase 2 | Belgium | 09 Dec 2021 | |
Merkel Cell Carcinoma | Phase 2 | Netherlands | 09 Dec 2021 | |
Merkel Cell Carcinoma | Phase 2 | Switzerland | 09 Dec 2021 | |
Merkel Cell Carcinoma | Phase 2 | United Kingdom | 09 Dec 2021 | |
metastatic non-small cell lung cancer | Phase 2 | United States | 09 Dec 2021 |
Not Applicable | - | - | PAC-Net | ekmfedbqvg(xbpdxpgchv) = bmdpbqlvmw gkagralrrq (tzihiqapum ) View more | - | 09 Jun 2024 | |
PAC-Net (U-Net) | ekmfedbqvg(xbpdxpgchv) = adioqcowja gkagralrrq (tzihiqapum ) View more | ||||||
Phase 2 | 52 | 89-Zr-Crefmirlimab Berdoxam (CD8 cell immunohistochemistry) | pjoomdwvve(ypllxzzcqj) = myiqdtivok mqjzcleccl (kdsiokldbh, 114 - 461) | Positive | 07 Nov 2022 | ||
NCT03107663 (Pubmed) Manual | Phase 1 | 15 | ohcmniunrd(yirzgaoums) = No drug-related adverse events or abnormal laboratory results were noted except for a transient increase in anti-drug antibodies in 1 subject vaniumaceg (pkngsqntwh ) | Positive | 19 Aug 2021 | ||
Phase 1 | 3 | (<sup>89</sup>Zr-IAB22M2C) | dbvxnnioco(umwbnpfkwr) = No immediate or delayed side effects were seen with 89Zr-IAB22M2C priaaisybd (hmvznyawvg ) | - | 01 Jun 2018 | ||
Not Applicable | - | - | npjurmdcum(oyvyxtevca) = pzvuwtmiax dmdwdnnzbk (yvjktnmzwu ) View more | - | 08 Dec 2016 |