Last update 20 Jun 2024

Invopressin

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
[Phe^2,Ile^3,Dab(PhAc-D-Tyr(Me)-Phe-Gln-Asn-Ala-Pro-Arg-iGln-Lys(Ac)-Epsilon-Lys)^8]vasopressin, OCE-205, OCE205
Target
Mechanism
AVPR1A modulators(Vasopressin V1a receptor modulators)
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationOrphan Drug (US)

Structure

Molecular FormulaC110H161N31O27S2
InChIKeyGWRWHCLGMDWCIR-FQEGLUSVSA-N
CAS Registry1488411-60-4

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Kidney InjuryPhase 2
US
28 Apr 2022
Acute Kidney InjuryPhase 2
CA
28 Apr 2022
AscitesPhase 2
US
28 Apr 2022
AscitesPhase 2
CA
28 Apr 2022
FibrosisPhase 2
US
28 Apr 2022
FibrosisPhase 2
CA
28 Apr 2022
Hepatorenal SyndromePhase 2
US
28 Apr 2022
Hepatorenal SyndromePhase 2
CA
28 Apr 2022
End Stage Liver DiseasePhase 1--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
64
lqznphchgt(pgbtdlbwoa) = The most frequent adverse events were abdominal pain, abnormal gastrointestinal sounds, and diarrhea, with no reported cases of mesenteric ischemia. Adverse events were generally mild or moderate in severity. copjgznwdz (pchwpruvxy )
Positive
06 Nov 2022
Placebo
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Clinical Trial

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Approval

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Regulation

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