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Last update 11 Oct 2025
PM-1016
Last update 11 Oct 2025
Overview
Basic Info
Drug Type Gene therapy |
Synonyms PM 1016, PM1016 |
Target |
Action inhibitors, stimulants |
Mechanism IL-2 inhibitors(Interleukin-2 inhibitors), Cell death stimulants |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseIND Approval |
First Approval Date- |
Regulation- |
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Related
3
Clinical Trials associated with PM-1016CTR20222200
评价PM8002注射液联合PM1016注射液二线治疗晚期肝细胞癌受试者的初步疗效及安全性的Ib期临床试验
[Translation] A phase Ib clinical trial to evaluate the preliminary efficacy and safety of PM8002 injection combined with PM1016 injection as a second-line treatment for subjects with advanced hepatocellular carcinoma
CTR20210764
评价编码 TNF-α 和 IL-2 的溶瘤腺病毒 PM1016 在晚期恶性实体瘤受试者中的耐受性、安全性及初步疗效的 I 期临床试验及在晚期恶性实体瘤中考察初步疗效的 IIa 期临床试验
[Translation] A Phase I clinical trial to evaluate the tolerability, safety and preliminary efficacy of oncolytic adenovirus PM1016 encoding TNF-α and IL-2 in subjects with advanced malignant solid tumors and a Phase IIa clinical trial to investigate preliminary efficacy in subjects with advanced malignant solid tumors
ChiCTR2100045182
Phase I clinical trial evaluating the tolerability, safety, and initial efficacy of oncolytic adenovirus PM1016 encoding TNF-α and IL-2 in subjects with advanced malignant solid tumors and phase IIa clinical trial evaluating initial efficacy in subjects with advanced malignant solid tumors
100 Clinical Results associated with PM-1016
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100 Translational Medicine associated with PM-1016
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100 Patents (Medical) associated with PM-1016
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100 Deals associated with PM-1016
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Malignant Solid Neoplasm | Phase 2 | China | 23 Jun 2021 | |
| Advanced Malignant Solid Neoplasm | Phase 2 | China | 23 Jun 2021 | |
| Advanced Malignant Solid Neoplasm | Phase 2 | China | 23 Jun 2021 | |
| Hepatocellular Carcinoma | IND Approval | China | 18 Aug 2022 |
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