Last update 01 Nov 2024

Rocakinogene Sifuplasmid

Overview

Basic Info

Drug Type
Personalized antigen vaccine, Therapeutic vaccine
Synonyms
Rocakinogene Sifuplasmid, INO-9012
Target-
Mechanism
Immunostimulants
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
GlioblastomaPhase 2
US
31 May 2018
Locally Advanced Urothelial CarcinomaPhase 2
US
24 May 2018
Transitional Cell CarcinomaPhase 2
US
24 May 2018
Transitional Cell CarcinomaPhase 2
ES
24 May 2018
Head and Neck NeoplasmsPhase 2
US
26 Jun 2017
Human Papillomavirus InfectionPhase 2
US
26 Jun 2017
Human Papillomavirus InfectionPhase 2
US
26 Jun 2017
Squamous Intraepithelial Lesions of the CervixPhase 2
US
26 Jun 2017
Urogenital AbnormalitiesPhase 2
US
26 Jun 2017
Vulvar DiseasesPhase 2
US
26 Jun 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
24
isckkyrtfi(zucjktdgwc) = elednzwtfb wdpiqxnchj (mgqnxrhxsd )
Positive
01 Nov 2022
Phase 1/2
Glioblastoma
First line
52
electroporation+cemiplimab+Temozolomide+Radiation Therapy+INO-5401+INO-9012
(unmethylated MGMT)
rnwwikwzvb(glknlkzwca) = akljhpgexb cnhyskgasq (avkjnernoo, 14.5 - 19.8)
Positive
02 Jun 2022
electroporation+cemiplimab+Temozolomide+Radiation Therapy+INO-5401+INO-9012
(methylated MGMT)
rnwwikwzvb(glknlkzwca) = rcvjtepqhu cnhyskgasq (avkjnernoo, 18.4 - NR)
Phase 1/2
Glioblastoma
First line
52
(Cohort A:32 pts,MGMT unmethylated;Cohort B:20 pts,MGMT methylated)
xmuvjzrvxg(qxiqqgjfku) = 1/69 related to the combination therapy, Grade 1 pyrexia. mchzwhhwyw (ijpnzjnrrj )
Positive
29 May 2020
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Clinical Trial

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Approval

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Regulation

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