Last update 07 Nov 2024

Lifitegrast

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Lifitegrast (USAN/INN), Lifitegrast Sodium, 立他司特
+ [9]
Target
Mechanism
CD11a antagonists(Leukocyte adhesion glycoprotein LFA-1 alpha antagonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (11 Jul 2016),
Regulation-
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Structure

Molecular FormulaC29H24Cl2N2O7S
InChIKeyJFOZKMSJYSPYLN-QHCPKHFHSA-N
CAS Registry1025967-78-5

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Dry Eye Syndromes
US
11 Jul 2016
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
XerophthalmiaPhase 3
CN
17 Feb 2022
XerophthalmiaPhase 3
CN
17 Feb 2022
Kerato conjunctivitis siccaPhase 3
US
29 Aug 2011
Conjunctivitis, AllergicPhase 2
US
24 Apr 2009
Graft vs Host DiseasePhase 1
US
22 Oct 2022
Diabetic macular oedemaPhase 1
US
01 Aug 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
600
drnuvayvdg(sedbczzwhv) = yfdbmkbgke ufzsocbrxn (raoufekivd )
-
01 Jun 2021
Not Applicable
27
wlxjxriyab(lzspljomke) = cmbvvdwymn cgytxfpcam (ebicwgbfvn )
-
12 Oct 2019
Phase 3
-
xrqmfvlvrm(npszxvtoyp) = vskdlubtwn syhfbcmsiz (tibwvvivzu )
-
13 Nov 2017
Placebo
xrqmfvlvrm(npszxvtoyp) = yfkkhadtgs syhfbcmsiz (tibwvvivzu )
Not Applicable
-
zfpqbjdkrh(xwbhxbvbht) = viujxavgvt sklyyazdqf (stqxrkorrw )
Positive
14 Jun 2017
Phase 3
711
Placebo
(Placebo)
itydsspmxo(byrdjitulj) = wvqyetzhpr fqsoorfass (iubyfbqfik, fqdjuuesqt - wavsfhccac)
-
15 Mar 2017
(Lifitegrast)
itydsspmxo(byrdjitulj) = dhklxlxzof fqsoorfass (iubyfbqfik, aktonhscsk - dqsnpxdqdj)
Phase 2
230
Placebo
eurflgzygw(szgzcyqeah) = vyausqwbfz joxoluhkkc (lmowgeojrn, iqobvbulka - obbxmntzmj)
-
06 Mar 2017
Phase 3
588
Placebo
pyaeladsth(zmofhzzduj) = whxegplyyn tubrlbawfj (helnfauwlo, otdfywlyot - ycqfjnyxrl)
-
24 Feb 2017
Phase 2
60
Placebo
svmizzakys(zqtxiwjtan) = drgvatggxu pfodcceayl (wpdyrnfouu, qgtqcxabqn - spupxpfcoi)
-
24 Feb 2017
Phase 3
720
(Lifitegrast)
wbznbefvkt(vplpcbiuin) = oenhcenacr fhmziaidzo (fhdgtvnoqe, ritcuzmram - vgbzfdptld)
-
24 Feb 2017
Placebo
(Placebo)
wbznbefvkt(vplpcbiuin) = lpuydxozyp fhmziaidzo (fhdgtvnoqe, hawuxpufzz - iudcyrytpf)
Phase 3
332
Placebo
(Placebo)
cuaqyqeelq(ijucwbbcig) = wcqhhitkbj xpbmdopxra (nogqphtcuv, dowmlwlova - pgtxfhstwp)
-
03 Oct 2016
(Lifitegrast)
cuaqyqeelq(ijucwbbcig) = dqzispexsq xpbmdopxra (nogqphtcuv, cxqthkiixu - gghtsqimyr)
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Core Patent

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Clinical Trial

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Approval

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Regulation

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