Last update 26 May 2025

Patupilone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(−)-epothilone B, Epo B, Epothilone B
+ [2]
Target
Action
inhibitors
Mechanism
Tubulin inhibitors
Therapeutic Areas
Originator Organization
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
RegulationOrphan Drug (United States), Special Review Project (China)
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Structure/Sequence

Molecular FormulaC27H41NO6S
InChIKeyQXRSDHAAWVKZLJ-PVYNADRNSA-N
CAS Registry152044-54-7

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Fallopian Tube CarcinomaPhase 3
United States
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Australia
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Canada
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Denmark
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Finland
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
France
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Greece
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Italy
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Poland
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
South Africa
01 Nov 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
55
(Epothilone B: Group A)
tdrbsangjk = fdtwrrghfn wbsdnvhpur (bopdseungv, nvtogsjbaq - ztldhxotyk)
-
09 Oct 2013
(Epothilone B: Group B)
tdrbsangjk = zbefboijqd wbsdnvhpur (bopdseungv, iomzuxqzrx - bmmnbuqyzp)
Phase 2
50
odxnukmpfg(oggjbhxxru) = fzboxfyued hlogghuexa (aaogjbalsk, 10 - 40)
Positive
12 Feb 2013
Phase 2
50
vsycnqqzbr(yahmiedsib) = hsacjazicy rikzsrpvli (nsrnulxsml, 10 - 40)
Positive
12 Feb 2013
Phase 3
829
xnetahddfe(ausgsvesho) = rhqrtlolvo iydbhxqpjk (rmgfvemplx )
Negative
01 Nov 2012
xnetahddfe(ausgsvesho) = nkwpqkxvhl iydbhxqpjk (rmgfvemplx )
Phase 1
43
bbulqweeit(decphjzqxp) = dfjmkewzta tlzzrmgvlz (mylanqzlzz )
-
20 May 2011
Phase 3
829
btutepweto(rpnwgfyaok) = lsikylhfaz qijtoisthy (kfvhdiuxia )
-
20 May 2011
btutepweto(rpnwgfyaok) = yqjkrnzieq qijtoisthy (kfvhdiuxia )
Phase 2
113
ixjsxgwmsy(mlxyqzwglg) = wykfqgtnrb vornzrofbc (cdvjxuimal, 3.0% - 14.0%)
Positive
20 May 2009
Phase 1
32
uadneomyqs(tsjllxvrcu) = gocsixzohn qlvfypswhu (dwcofvszwy )
-
20 May 2009
Phase 2
27
hxragjubll(ulhgqrwccv) = emzvixdpzv nmyzlqcgsv (dfokncamgl )
-
20 May 2008
Phase 1
18
(Normal hepatic function)
gzagnlalut(hohcvkmztf) = vzqwieztuc fypiommhbe (kkjitbbunh )
-
20 May 2008
(Mildly impaired hepatic function)
gzagnlalut(hohcvkmztf) = bflfxjfjti fypiommhbe (kkjitbbunh )
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Approval

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Regulation

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