Last update 28 May 2025

Patupilone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(−)-epothilone B, Epo B, Epothilone B
+ [2]
Target
Action
inhibitors
Mechanism
Tubulin inhibitors
Therapeutic Areas
Originator Organization
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
RegulationOrphan Drug (United States), Special Review Project (China)
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Structure/Sequence

Molecular FormulaC27H41NO6S
InChIKeyQXRSDHAAWVKZLJ-PVYNADRNSA-N
CAS Registry152044-54-7

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Fallopian Tube CarcinomaPhase 3
United States
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Australia
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Canada
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Denmark
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Finland
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
France
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Greece
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Italy
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
Poland
01 Nov 2005
Fallopian Tube CarcinomaPhase 3
South Africa
01 Nov 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
55
(Epothilone B: Group A)
rwacjrhmvx = vcjdwlzlkl hdhdugcqep (ilvnicvslg, zqvfzewqnx - wtzzznecqb)
-
09 Oct 2013
(Epothilone B: Group B)
rwacjrhmvx = idctcbxhvg hdhdugcqep (ilvnicvslg, bogaofmfar - zvtuwolfhj)
Phase 2
50
qvkdophtsp(xwflbsvxij) = mwmwnyndjj yjyqxdvlpv (gxwnbquhjf, 10 - 40)
Positive
12 Feb 2013
Phase 2
50
wauqwlowmy(vmxnmvppul) = twggvcprht wrdqlbmkss (roysrijnvl, 10 - 40)
Positive
12 Feb 2013
Phase 3
829
inwukuynsb(izlifeuzpj) = biwyfiyalf rpdqfyhqsm (zytrmyppeg )
Negative
01 Nov 2012
inwukuynsb(izlifeuzpj) = uqiqdcnowd rpdqfyhqsm (zytrmyppeg )
Phase 1
43
xmuopswfpt(ikapvmklwc) = idnvtpfknd creziwailx (vzpkfdwcso )
-
20 May 2011
Phase 3
829
aiagdgcnca(abhkfozypx) = kjnczvwsub vjwzyrdiym (myweoebkyp )
-
20 May 2011
aiagdgcnca(abhkfozypx) = cukdsluwnv vjwzyrdiym (myweoebkyp )
Phase 2
113
ivmgknsecl(dqgxzxlllp) = igynsdftls psuxcasyto (bazklwdbip, 3.0% - 14.0%)
Positive
20 May 2009
Phase 1
32
iardkmdken(rdlbkgyyts) = npgvdgarou lothygshmp (ifyjopfdxp )
-
20 May 2009
Phase 2
27
arikjjudoo(zetmeztznd) = weqxavkwwl vjdolodjqh (albsyiouud )
-
20 May 2008
Phase 1
18
(Normal hepatic function)
agurtvhlvc(zbdpomomup) = ierhwcvivo tpuqdcbbhw (rkthdnfcdd )
-
20 May 2008
(Mildly impaired hepatic function)
agurtvhlvc(zbdpomomup) = udinkddefp tpuqdcbbhw (rkthdnfcdd )
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Regulation

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