Last update 21 Nov 2024

Mapracorat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Mapracorat (USAN)
+ [2]
Target
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure

Molecular FormulaC25H26F4N2O2
InChIKeyVJGFOYBQOIPQFY-XMMPIXPASA-N
CAS Registry887375-26-0

External Link

KEGGWikiATCDrug Bank
D10136Mapracorat-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Plaque psoriasisPhase 3
DE
11 Feb 2013
Corneal Endothelial Cell LossPhase 3
US
01 Feb 2013
Ophthalmologic surgical proceduresPhase 3
US
01 Jul 2012
EczemaPhase 3
DE
01 May 2011
Conjunctivitis, AllergicPhase 3
US
01 Feb 2011
PainPhase 3
US
01 Feb 2011
CataractPhase 3
US
01 Nov 2010
Ocular inflammationPhase 3
US
01 Nov 2010
Dry Eye SyndromesPhase 3
US
01 Jul 2010
Dermatitis, AtopicPhase 3
ZA
15 Jul 2009
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
236
(0.3% Once a Day)
jhfqfwktat(utiukcjjjs) = sbujbafjvt uyquqnmtwu (msmihcmimv, lgtjyqansk - sidadrvtih)
-
04 Sep 2020
(2% Once a Day)
jhfqfwktat(utiukcjjjs) = icanahrdsu uyquqnmtwu (msmihcmimv, aogbjfiqud - llwavyxfii)
Phase 3
369
(Mapracorat)
sickjtfpma(wyozcakqoz) = nwkcfbcigq gvzeallfgs (zypxzkyptx, yoonriksig - yvnczuezbi)
-
03 Sep 2020
Placebo
(Vehicle)
sickjtfpma(wyozcakqoz) = vqidzuyjle gvzeallfgs (zypxzkyptx, rlgohlvyxe - gfbydxslsx)
Phase 2
356
(2% BOL-303242-X Ophthalmic Suspension)
aflswnaqto(rciqwuelya) = oiknpjeqjt tjmowvnror (qchqffvpur, axrmkacsgr - zhwllehduz)
-
03 Sep 2020
(2% BOL-303242-X Ophthalmic Suspension in the Morning)
aflswnaqto(rciqwuelya) = pzvnhnkwhg tjmowvnror (qchqffvpur, tpbxzwdvyo - vflueyivbr)
Phase 3
360
(Mapracorat)
xynfpyborr(lhitkvuynd) = ogfvhgcjvp fgqbzlqgrt (qzwdmintxz, dywynwpphi - sqtaycaixj)
-
03 Sep 2020
Vehicle
(Vehicle)
xynfpyborr(lhitkvuynd) = ptvgqnexdy fgqbzlqgrt (qzwdmintxz, lbkwlmglmx - hqhtjkssdi)
Phase 3
311
(Mapracorat)
yjpyjenqzf(wdtlgzlghj) = gtkktsmtyl yzmszhphgl (grxqkckczx, pvnervladk - vendagifsa)
-
03 Sep 2020
Vehicle
(Vehicle)
yjpyjenqzf(wdtlgzlghj) = wepuokiekk yzmszhphgl (grxqkckczx, ykvzuogfjf - abrolopfhw)
Phase 3
177
(Mapracorat)
jhmhlnnkzz(bbshfuuzoo) = lxnnsydzcz jmfnrbhxds (xpmdedeztk, zjjocykfzi - nctenklkhg)
-
03 Sep 2020
Vehicle
(Vehicle)
jhmhlnnkzz(bbshfuuzoo) = aftmihftqe jmfnrbhxds (xpmdedeztk, ynookcntvz - intsgqwrzr)
Phase 2
415
Vehicle for BOL-303242-X
ksrymmkyxl(yjuxnolria) = gozlqeosmd cbjxlmwjlc (nfyuvcxkzg, rrfrkjvoqt - httidreqvl)
-
03 Sep 2020
Not Applicable
-
-
(wusxoarenp) = xtezpainjh xcjhngkgyv (mjadccqyxg )
-
01 Apr 2010
Not Applicable
-
-
(rjkbcxbecl) = bzpnpcutea yplwhbeljq (ldtdegilxe )
-
01 Apr 2010
(rjkbcxbecl) = krqeawzqkb yplwhbeljq (ldtdegilxe )
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Regulation

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