Drug Type Small molecule drug |
Synonyms Mapracorat (USAN) + [2] |
Target |
Mechanism GR agonists(Glucocorticoid receptor agonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC25H26F4N2O2 |
InChIKeyVJGFOYBQOIPQFY-XMMPIXPASA-N |
CAS Registry887375-26-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10136 | Mapracorat | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Plaque psoriasis | Phase 3 | DE | 11 Feb 2013 | |
Corneal Endothelial Cell Loss | Phase 3 | US | 01 Feb 2013 | |
Ophthalmologic surgical procedures | Phase 3 | US | 01 Jul 2012 | |
Eczema | Phase 3 | DE | 01 May 2011 | |
Conjunctivitis, Allergic | Phase 3 | US | 01 Feb 2011 | |
Pain | Phase 3 | US | 01 Feb 2011 | |
Cataract | Phase 3 | US | 01 Nov 2010 | |
Ocular inflammation | Phase 3 | US | 01 Nov 2010 | |
Dry Eye Syndromes | Phase 3 | US | 01 Jul 2010 | |
Dermatitis, Atopic | Phase 3 | ZA | 15 Jul 2009 |
Phase 2 | 236 | (0.3% Once a Day) | jhfqfwktat(utiukcjjjs) = sbujbafjvt uyquqnmtwu (msmihcmimv, lgtjyqansk - sidadrvtih) View more | - | 04 Sep 2020 | ||
(2% Once a Day) | jhfqfwktat(utiukcjjjs) = icanahrdsu uyquqnmtwu (msmihcmimv, aogbjfiqud - llwavyxfii) View more | ||||||
Phase 3 | 369 | (Mapracorat) | sickjtfpma(wyozcakqoz) = nwkcfbcigq gvzeallfgs (zypxzkyptx, yoonriksig - yvnczuezbi) View more | - | 03 Sep 2020 | ||
Placebo (Vehicle) | sickjtfpma(wyozcakqoz) = vqidzuyjle gvzeallfgs (zypxzkyptx, rlgohlvyxe - gfbydxslsx) View more | ||||||
Phase 2 | 356 | (2% BOL-303242-X Ophthalmic Suspension) | aflswnaqto(rciqwuelya) = oiknpjeqjt tjmowvnror (qchqffvpur, axrmkacsgr - zhwllehduz) View more | - | 03 Sep 2020 | ||
(2% BOL-303242-X Ophthalmic Suspension in the Morning) | aflswnaqto(rciqwuelya) = pzvnhnkwhg tjmowvnror (qchqffvpur, tpbxzwdvyo - vflueyivbr) View more | ||||||
Phase 3 | 360 | (Mapracorat) | xynfpyborr(lhitkvuynd) = ogfvhgcjvp fgqbzlqgrt (qzwdmintxz, dywynwpphi - sqtaycaixj) View more | - | 03 Sep 2020 | ||
Vehicle (Vehicle) | xynfpyborr(lhitkvuynd) = ptvgqnexdy fgqbzlqgrt (qzwdmintxz, lbkwlmglmx - hqhtjkssdi) View more | ||||||
Phase 3 | 311 | (Mapracorat) | yjpyjenqzf(wdtlgzlghj) = gtkktsmtyl yzmszhphgl (grxqkckczx, pvnervladk - vendagifsa) View more | - | 03 Sep 2020 | ||
Vehicle (Vehicle) | yjpyjenqzf(wdtlgzlghj) = wepuokiekk yzmszhphgl (grxqkckczx, ykvzuogfjf - abrolopfhw) View more | ||||||
Phase 3 | 177 | (Mapracorat) | jhmhlnnkzz(bbshfuuzoo) = lxnnsydzcz jmfnrbhxds (xpmdedeztk, zjjocykfzi - nctenklkhg) View more | - | 03 Sep 2020 | ||
Vehicle (Vehicle) | jhmhlnnkzz(bbshfuuzoo) = aftmihftqe jmfnrbhxds (xpmdedeztk, ynookcntvz - intsgqwrzr) View more | ||||||
Phase 2 | 415 | Vehicle for BOL-303242-X | ksrymmkyxl(yjuxnolria) = gozlqeosmd cbjxlmwjlc (nfyuvcxkzg, rrfrkjvoqt - httidreqvl) View more | - | 03 Sep 2020 | ||
Not Applicable | - | - | (wusxoarenp) = xtezpainjh xcjhngkgyv (mjadccqyxg ) | - | 01 Apr 2010 | ||
Not Applicable | - | - | (rjkbcxbecl) = bzpnpcutea yplwhbeljq (ldtdegilxe ) | - | 01 Apr 2010 | ||
(rjkbcxbecl) = krqeawzqkb yplwhbeljq (ldtdegilxe ) |