Last update 21 Nov 2024

Namodenoson

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2-Chloro-N6--(3-iodobenzyl)adenosine-5'-N-methyluronamide, Cl-IB-MECA, Namodenoson (USAN/INN)
+ [2]
Target
Mechanism
A3R agonists(Adenosine A3 receptor agonists)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (EU), Fast Track (US)
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Structure

Molecular FormulaC18H18ClIN6O4
InChIKeyIPSYPUKKXMNCNQ-PFHKOEEOSA-N
CAS Registry163042-96-4

External Link

KEGGWikiATCDrug Bank
D11128--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Hepatocellular CarcinomaPhase 3
RO
15 Mar 2023
Advanced Hepatocellular CarcinomaPhase 3
IL
15 Mar 2023
Advanced Hepatocellular CarcinomaPhase 3
BA
15 Mar 2023
Advanced Hepatocellular CarcinomaPhase 3
SK
15 Mar 2023
Advanced Hepatocellular CarcinomaPhase 3
MD
15 Mar 2023
Advanced Hepatocellular CarcinomaPhase 3
US
15 Mar 2023
Advanced Hepatocellular CarcinomaPhase 3
RS
15 Mar 2023
Advanced Hepatocellular CarcinomaPhase 3
PL
15 Mar 2023
Advanced Hepatocellular CarcinomaPhase 3
BG
15 Mar 2023
Hepatocellular CarcinomaPhase 3
CN
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
znswtxjwrz(wkyqusanxj) = zyuebjikud avwurpfjlb (ilymfkbbtf )
Positive
02 Sep 2022
Placebo
znswtxjwrz(wkyqusanxj) = dujocfxylj avwurpfjlb (ilymfkbbtf )
Phase 2
78
(CF102)
faxgzgwiwh(kvrdkhtlam) = hhemafxvea boykzljeus (hxeraaoqhw, poornsurcm - vhgyhtlvvi)
-
29 Dec 2021
Placebo
(Placebo Tablets of CF102)
faxgzgwiwh(kvrdkhtlam) = xjtbxhprbg boykzljeus (hxeraaoqhw, mtyragvkch - tmvyypqzfx)
Phase 2
60
ibrtcmmmnq(invwurkmvn) = uahizepewx faumlbwkwc (xqttvnobvd )
-
20 Oct 2021
Placebo
ibrtcmmmnq(invwurkmvn) = jvhobxzveq faumlbwkwc (xqttvnobvd )
Phase 2
78
(jrmtbsmkjd) = qhkraoifaz ylscdccpot (gbppuguqgr )
Positive
07 Jan 2021
Placebo
(jrmtbsmkjd) = rbtmqvsnxc ylscdccpot (gbppuguqgr )
Phase 2
78
(uiincfioyb) = ylqvwlauec qdgkblkldm (biobvgetxh )
Positive
02 Jun 2019
placebo
(uiincfioyb) = mhvandbnet qdgkblkldm (biobvgetxh )
Phase 1/2
32
(Cohort 1 CF102 1 mg qd)
mrgqkzpaow(txyqquupsa) = sasegkfpml rfyybcpyak (vkiksxyuqd, rsrwiqwbdy - vwsrvtxkei)
-
15 Apr 2015
(Cohort 2 CF102 1 mg Bid)
mrgqkzpaow(txyqquupsa) = sppgvelccu rfyybcpyak (vkiksxyuqd, jsootgfchq - stunllropq)
Phase 1/2
19
(CF102 1mg)
(kgpffinmoi) = padduwlwps eabthxlllu (uojsuxabup, iozdjuqaav - ngcrhfutet)
-
27 Feb 2015
(CF102 5mg)
(kgpffinmoi) = wyqlihqize eabthxlllu (uojsuxabup, ljrklpnagb - jtoqmawskg)
Phase 1/2
19
(arvjnshpec) = srynirhvhu lxvofwsmeb (ynicfmxdfe )
-
01 Jan 2013
(arvjnshpec) = obxjepajrk lxvofwsmeb (ynicfmxdfe )
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Regulation

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