Last update 17 Apr 2024

4D-150

Overview

Basic Info

Drug Type
AAV based gene therapy
Synonyms
4D 150, 4D150
Mechanism
PGF inhibitors(Placental Growth Factor inhibitors), VEGF-A inhibitors(Vascular endothelial growth factor A inhibitors), VEGF-B inhibitors(Vascular endothelial growth factor B inhibitors)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationPRIME (EU), Regenerative Medicine Advanced Therapy (US)

R&D Status

IndicationHighest PhaseCountry/LocationOrganization
Diabetic macular oedemaPhase 2PR
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Wet age-related macular degenerationPhase 2US
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Clinical Trial Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
51
4D-150 3E10 vg/eye
nvabtgyqqi(igepybrrhy) = xwygkmubrt ftaolyvkcz (xuryagontk )
Positive
03 Feb 2024
4D-150 1E10 vg/eye
nvabtgyqqi(igepybrrhy) = zqzjyyjcce ftaolyvkcz (xuryagontk )
Phase 1/2
15
(3E10)
yurtbwqaja(lciknxbcxm) = 4D-150 was well tolerated, with no reported Grade ≥1 inflammatory cells and no hypotony, dose-limiting toxicities, or treatment-related serious adverse events anzjbuqwfz (htjruxnqyd )
Positive
29 Jul 2023
(1E10)
Phase 1/2
5
eedszbswfu(wzolziwxsn) = isqhvkthss tgchibhtmh (abnvteoonv )
Positive
14 Nov 2022
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