Last update 30 Oct 2025

SYD-1875

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
Anti-5T4 antibody drug conjugate, SYD 1875
Target
5T4 x DNA
Action
inhibitors
Mechanism
5T4 inhibitors(Trophoblast glycoprotein inhibitors), DNA inhibitors(DNA inhibitors)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
NeoplasmsSolid tumor
Originator Organization
Synthon BVSynthon BV
Active Organization-
Inactive Organization
Byondis BVByondis BVSynthon BVSynthon BV
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Structure/Sequence

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Related

1
Clinical Trials associated with SYD-1875
NCT04202705
/ CompletedPhase 1
A First-in-human Dose-escalation and Expansion Study With the Antibody-drug Conjugate SYD1875 to Evaluate the Safety, Pharmacokinetics and Efficacy in Patients With 5T4-expressing Locally Advanced or Metastatic Solid Tumours
100 Clinical Results associated with SYD-1875
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100 Translational Medicine associated with SYD-1875
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100 Patents (Medical) associated with SYD-1875
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100 Deals associated with SYD-1875
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Solid tumorPhase 1
Belgium
Byondis BVByondis BV
28 Feb 2020
Solid tumorPhase 1
Belgium
Synthon BVSynthon BV
28 Feb 2020
Solid tumorPhase 1
France
Synthon BVSynthon BV
28 Feb 2020
Solid tumorPhase 1
France
Byondis BVByondis BV
28 Feb 2020
NeoplasmsDiscovery
Netherlands
Synthon BVSynthon BV
28 Feb 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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