Last update 10 Dec 2024

Rosabulin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Rosabulin (USAN), STA-5312
Target
Tubulin
Mechanism
Tubulin inhibitors
Therapeutic Areas
Neoplasms
Active Indication
Neoplasms
Inactive Indication
Advanced Malignant Solid NeoplasmLeukemiaLymphoma+ [1]
Originator Organization
Madrigal Pharmaceuticals, Inc.Madrigal Pharmaceuticals, Inc.
Active Organization
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
Inactive Organization
Synta Pharmaceuticals Corp.Synta Pharmaceuticals Corp.
Drug Highest PhasePreclinical
First Approval Date-
Regulation-
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Structure

Molecular FormulaC22H16N4O2S
InChIKeyIZZYUABKZYIINT-UHFFFAOYSA-N
CAS Registry501948-05-6

Related

2
Clinical Trials associated with Rosabulin
NCT00276913 / CompletedPhase 1
A Phase I Study of STA-5312 Administered Weekly in Subjects With Advanced or Metastatic Solid Tumors
NCT00088101 / CompletedPhase 1
Phase I Trial of STA-5312 Administered on Alternate Weekdays Every Two Weeks to Patients With Hematological Malignancies and Patients With Solid Tumors
100 Clinical Results associated with Rosabulin
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100 Translational Medicine associated with Rosabulin
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100 Patents (Medical) associated with Rosabulin
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100 Deals associated with Rosabulin
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External Link

KEGGWikiATCDrug Bank
D06638---

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
US
Synta Pharmaceuticals Corp.Synta Pharmaceuticals Corp.
01 Jun 2004
LeukemiaPhase 1
US
Synta Pharmaceuticals Corp.Synta Pharmaceuticals Corp.
01 Feb 2004
LymphomaPhase 1
US
Synta Pharmaceuticals Corp.Synta Pharmaceuticals Corp.
01 Feb 2004
Metastatic Solid TumorPhase 1
US
Synta Pharmaceuticals Corp.Synta Pharmaceuticals Corp.
01 Feb 2004
NeoplasmsPreclinical
US
Dana-Farber Cancer Institute, Inc.Dana-Farber Cancer Institute, Inc.
01 Apr 2004
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
ASCO2006
Phase 1
Solid tumor
25
wcbyoqjiwn(jfzpwcsvwi) = anemia, fatigue, constipation, nausea, and anorexia vwnmfihbch (tlbxkeyujh )
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-
20 Jun 2006
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Clinical Trial

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Approval

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Regulation

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