EXG-34217

BALTIMORE, Jan. 26, 2023 (GLOBE NEWSWIRE) -- Elixirgen Therapeutics, Inc., a clinical-stage biotechnology company focused on the discovery, development and commercialization of therapies using its controllable self-replicating RNA (c-srRNA) platform, today announced that it has entered a memorandum of understanding with Hitachi Global Life Solutions, Inc. (Hitachi GLS) for the development of Micro GMP suites to facilitate cell therapy administration. Elixirgen Therapeutics is currently conducting a Phase 1/2 trial (NCT04211714) with lead asset, EXG-34217, an autologous cell therapy to treat patients with telomere biology disorders with bone marrow failure. The collection, processing and infusion of targeted cells are all performed at the clinical site. The planned collaboration with Hitachi would result in the development of Micro GMP suites, which are a next-generation method for patients to receive cell therapy treatment compared to the current standard. “We are pleased to enter this agreement with a well-known partner such as Hitachi GLS to develop Micro GMP suites that will provide solutions for some of the big challenges in how cell therapy is currently administered. Key issues that facilities face include significant logistical complexity, difficulty in scaling up and prolonged timelines from cell collection to infusion,” said Akihiro Ko, chief executive officer of Elixirgen Therapeutics. “The development of these Micro GMP suites would allow reductions in costs as well as timelines. We look forward to working with Hitachi GLS on streamlining the overall cell therapy process for better patient outcomes.” About Elixirgen Therapeutics, Inc. Elixirgen Therapeutics, Inc. is a clinical-stage biotechnology company focused on the discovery, development and commercialization of therapies using its controllable self-replicating RNA (c-srRNA) platform. The company has two products in Phase 1/2 clinical trials (NCT04211714 and NCT04863131). For more information, visit ElixirgenTherapeutics.com. Forward-Looking Statements This press release may contain "forward-looking" statements. Actual results may differ materially from those set forth in this press release due to the risks and uncertainties inherent in pharmaceutical research and development. Any forward-looking statements in this press release speak only as of the date of this press release, and Elixirgen Therapeutics undertakes no obligation to update or revise the statements in the future, even if new information becomes available. Contact Media Relations: Slavena Salve Nissan, M.D. LifeSci Communications snissan@lifescicomms.com 718-483-4440

BALTIMORE, Dec. 21, 2022 (GLOBE NEWSWIRE) -- Elixirgen Therapeutics, Inc., a clinical-stage biotechnology company focused on the discovery, development and commercialization of therapies using its controllable self-replicating RNA (c-srRNA) platform, today announced the appointment of Jeffrey L. Cleland, Ph.D., to the Board of Directors to support the advancement of its technology in developing therapies for a broad spectrum of diseases including rare diseases, aging-related disorders and cancer. "We are pleased to welcome Dr. Cleland to our Board as we continue to design next-generation RNA therapeutics with our proprietary technologies. His decades of expertise across the scientific and financial aspects of the industry will be invaluable to our clinical and business development strategies," said Akihiro Ko, chief executive officer of Elixirgen Therapeutics. "We look forward to working with Dr. Cleland as we continue to advance the EXG-34217 program in telomere biology disorders with bone marrow failure and explore other ways our technology can be harnessed to develop therapies for patients in need.” Dr. Cleland has 30 years of industry experience and currently serves as chairman, president and chief executive officer of Ashvattha Therapeutics. He also serves on the boards of BIO, Exicure and Zylem, and holds advisory roles with small emerging biotechnology companies. Previously, Dr. Cleland worked at Genentech, Inc. for more than a decade, where he served in product development and manufacturing roles. He has also served as CEO of Versartis and Graybug Vision. He has held executive management positions at several companies and brings to the team experience in drug development and late-stage research, including the successful approval of two drugs, Herceptin® and Nutropin Depot®, as well as early work on Lucentis®, Avastin® and Kadcyla®. He has authored more than 100 articles and four books and holds several issued patents. Dr. Cleland earned a B.S. in chemical engineering from the University of California, Davis, and a Ph.D. in chemical engineering from the Massachusetts Institute of Technology. Dr. Cleland added, "I’m eager to join the Board as Elixirgen Therapeutics continues to demonstrate how their novel technology has the potential to be a key player in the rapidly-evolving RNA space. Designed with safety in mind and with several key benefits including better control of gene expression, the platform has the versatility to be used across multiple therapeutic areas. I look forward to working with the Elixirgen Therapeutics team at this pivotal time in the Company’s growth." About Elixirgen Therapeutics, Inc. Elixirgen Therapeutics, Inc. is a clinical-stage biotechnology company focused on the discovery, development and commercialization of therapies using its controllable self-replicating RNA (c-srRNA) platform. The company has two products in Phase 1/2 clinical trials (NCT04211714 and NCT04863131). For more information, visit ElixirgenTherapeutics.com. Forward-Looking Statements This press release may contain "forward-looking" statements. Actual results may differ materially from those set forth in this press release due to the risks and uncertainties inherent in pharmaceutical research and development. Any forward-looking statements in this press release speak only as of the date of this press release, and Elixirgen Therapeutics undertakes no obligation to update or revise the statements in the future, even if new information becomes available. Contact Media Relations: Slavena Salve Nissan, M.D. LifeSci Communications snissan@lifescicomms.com 718-483-4440