Last update 01 Nov 2024

Varoglutamstat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
PBD-0701, PQ 912, PQ-912
+ [3]
Target
Mechanism
Glutaminyl-peptide cyclotransferase inhibitors
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (US)
Login to view timeline

Structure

Molecular FormulaC19H20N4O2
InChIKeyXHIKZWOEFZENIX-GOSISDBHSA-N
CAS Registry1276021-65-8

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Mild dementiaPhase 2
CN
26 Apr 2022
Mild dementiaPhase 2
CN
26 Apr 2022
Mild dementiaPhase 2
CN
26 Apr 2022
Mild cognitive disorderPhase 2
DK
06 Jul 2020
Mild cognitive disorderPhase 2
DK
06 Jul 2020
Mild cognitive disorderPhase 2
DE
06 Jul 2020
Mild cognitive disorderPhase 2
DE
06 Jul 2020
Mild cognitive disorderPhase 2
NL
06 Jul 2020
Mild cognitive disorderPhase 2
NL
06 Jul 2020
Mild cognitive disorderPhase 2
PL
06 Jul 2020
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
259
(total population)
sqeetwfaec(ujxibrchyi) = uoruarfvmp kglbcuurja (fjggjsipsp )
Positive
26 Oct 2024
Placebo
(total population)
-
Phase 2
Kidney Diseases
CCL2 Expression
-
xlojvypqse(bzshxpbuxe) = ztpykyxfqw viizikcjvv (uqzqjodvwc )
Positive
12 Sep 2024
Phase 2
250
tdhaphptxh(riuarqxuti) = oxcxqsfaxe ndngkidbky (cnkzfgcklf )
Positive
31 Jul 2022
Phase 2
120
jvrveqkotk(chldpwnbhk) = There was no significant difference between treatments in the number of subjects with (serious) adverse events, although there were slightly more patients with a serious adverse event in the PQ912 group compared to placebo. mrxtitlpoh (bstfowiqmy )
Positive
12 Oct 2018
Placebo
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free