Last update 21 Nov 2024

Tranilast

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
N-(3,4-Dimethoxycinnamoyl)anthranilic acid, Tranilast (JP17/USAN/INN)
+ [9]
Target
Mechanism
TGF-β inhibitors(Transforming growth factor beta inhibitors)
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
JP (15 Jun 1982),
RegulationOrphan Drug (EU)
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Structure

Molecular FormulaC18H17NO5
InChIKeyNZHGWWWHIYHZNX-UHFFFAOYSA-N
CAS Registry53902-12-8

External Link

KEGGWikiATCDrug Bank
D02027Tranilast

R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Conjunctivitis, Allergic
JP
29 Sep 1995
Conjunctivitis, Allergic
JP
29 Sep 1995
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
PterygiumPhase 3
BR
01 Jan 2015
Rheumatoid ArthritisDiscovery
CZ
01 Mar 2009
Rheumatoid ArthritisDiscovery
RS
01 Mar 2009
Rheumatoid ArthritisDiscovery
GB
01 Mar 2009
Rheumatoid ArthritisDiscovery
DE
01 Mar 2009
Rheumatoid ArthritisDiscovery
US
01 Mar 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
(Irradiation Group)
(bykeosgyqw) = anaokzyugy ulpbctwniq (ljnfpmdppn )
-
15 Oct 2023
Tranilast Pre-treated Irradiation Group
(bykeosgyqw) = lybuovvuwd ulpbctwniq (ljnfpmdppn )
Not Applicable
Dermatomyositis
TIF-g | NXP-2
111
riiirafvtx(uogxuprbdo) = vdfjqhhiwe vkhygbfpxv (xnutftguhb )
-
09 Nov 2012
Not Applicable
-
vcjnqvsahw(uoclsllvgk) = ovzreunzlu lkykaiixyl (inqoekdihu )
-
01 Nov 2006
Vehicle
vcjnqvsahw(uoclsllvgk) = pxdqeesypy lkykaiixyl (inqoekdihu )
Not Applicable
-
4
wzukazyqlq(ukseizwmqr) = dufirtoyme svqwdrldtp (bynasphtyw )
Positive
01 May 2006
Phase 3
-
32
kksgswhxor(tujunzdewg) = uxcbftqyts cmfecwlkcd (inhyxykoad )
-
01 Mar 2004
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Regulation

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