Drug Type Small molecule drug |
Synonyms N-(3,4-Dimethoxycinnamoyl)anthranilic acid, Tranilast (JP17/USAN/INN) + [9] |
Target |
Mechanism TGF-β inhibitors(Transforming growth factor beta inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date JP (15 Jun 1982), |
RegulationOrphan Drug (EU) |
Molecular FormulaC18H17NO5 |
InChIKeyNZHGWWWHIYHZNX-UHFFFAOYSA-N |
CAS Registry53902-12-8 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Conjunctivitis, Allergic | JP | 29 Sep 1995 | |
Conjunctivitis, Allergic | JP | 29 Sep 1995 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Pterygium | Phase 3 | BR | 01 Jan 2015 | |
Rheumatoid Arthritis | Discovery | CZ | 01 Mar 2009 | |
Rheumatoid Arthritis | Discovery | RS | 01 Mar 2009 | |
Rheumatoid Arthritis | Discovery | GB | 01 Mar 2009 | |
Rheumatoid Arthritis | Discovery | DE | 01 Mar 2009 | |
Rheumatoid Arthritis | Discovery | US | 01 Mar 2009 |
Not Applicable | - | - | (Irradiation Group) | (bykeosgyqw) = anaokzyugy ulpbctwniq (ljnfpmdppn ) View more | - | 15 Oct 2023 | |
Tranilast Pre-treated Irradiation Group | (bykeosgyqw) = lybuovvuwd ulpbctwniq (ljnfpmdppn ) View more | ||||||
Not Applicable | Dermatomyositis TIF-g | NXP-2 | 111 | riiirafvtx(uogxuprbdo) = vdfjqhhiwe vkhygbfpxv (xnutftguhb ) | - | 09 Nov 2012 | ||
Not Applicable | - | vcjnqvsahw(uoclsllvgk) = ovzreunzlu lkykaiixyl (inqoekdihu ) | - | 01 Nov 2006 | |||
Vehicle | vcjnqvsahw(uoclsllvgk) = pxdqeesypy lkykaiixyl (inqoekdihu ) | ||||||
Not Applicable | - | 4 | wzukazyqlq(ukseizwmqr) = dufirtoyme svqwdrldtp (bynasphtyw ) | Positive | 01 May 2006 | ||
Phase 3 | - | 32 | kksgswhxor(tujunzdewg) = uxcbftqyts cmfecwlkcd (inhyxykoad ) View more | - | 01 Mar 2004 |