Last update 19 Sep 2024

Tranilast

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
N-(3,4-Dimethoxycinnamoyl)anthranilic acid, Tranilast (JP17/USAN/INN)
+ [9]
Target
Mechanism
TGF-β inhibitors(Transforming growth factor beta inhibitors)
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
JP (15 Jun 1982),
RegulationOrphan Drug (EU)
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Structure

Molecular FormulaC18H17NO5
InChIKeyNZHGWWWHIYHZNX-UHFFFAOYSA-N
CAS Registry53902-12-8

External Link

KEGGWikiATCDrug Bank
D02027Tranilast

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Conjunctivitis, Allergic
JP
29 Sep 1995
Conjunctivitis, Allergic
JP
29 Sep 1995
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
PterygiumPhase 3
BR
01 Jan 2015
Rheumatoid ArthritisPhase 2
DE
01 Mar 2009
Rheumatoid ArthritisPhase 2
GB
01 Mar 2009
Rheumatoid ArthritisPhase 2
BG
01 Mar 2009
Rheumatoid ArthritisPhase 2
RS
01 Mar 2009
Rheumatoid ArthritisPhase 2
MX
01 Mar 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
Dermatomyositis
TIF-g | NXP-2
111
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-
09 Nov 2012
Not Applicable
-
4
gqtgidptbf(ttsspxtjwn) = hrpnmhaqfr orhyvxslda (fyrbzlvziq )
Positive
01 May 2006
Phase 3
-
32
oyidencust(frtmonctbv) = xblwnkzuzw aykgahlnsa (ttwypnumas )
-
01 Mar 2004
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Approval

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Regulation

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