Last update 15 Jul 2025

Aceclidine/Tropicamide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Tropicamide/aceclidine, PRX 100, PRX-100
Target
adrenergic receptor
Action
agonists
Mechanism
adrenergic receptor agonists(Adrenergic receptors agonists)
Therapeutic Areas
Eye Diseases
Active Indication-
Inactive Indication
Presbyopia
Originator Organization
LENZ Therapeutics, Inc.LENZ Therapeutics, Inc.
Active Organization-
Inactive Organization
LENZ Therapeutics, Inc.LENZ Therapeutics, Inc.
License Organization-
Drug Highest PhasePendingPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC17H20N2O2
InChIKeyBGDKAVGWHJFAGW-UHFFFAOYSA-N
CAS Registry1508-75-4
View All Structures (2)

Related

2
Clinical Trials associated with Aceclidine/Tropicamide
NCT03201562
/ CompletedPhase 2
A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia
NCT02554396
/ CompletedPhase 2
A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 (Aceclidine/Tropicamide) Ophthalmic Topical Formulation in the Treatment of Early to Moderate Presbyopia
100 Clinical Results associated with Aceclidine/Tropicamide
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100 Translational Medicine associated with Aceclidine/Tropicamide
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100 Patents (Medical) associated with Aceclidine/Tropicamide
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100 Deals associated with Aceclidine/Tropicamide
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
PresbyopiaPhase 2
United States
LENZ Therapeutics, Inc.LENZ Therapeutics, Inc.
01 Sep 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03201562 (CTgov)
Phase 2
Presbyopia
58
(Aceclidine+Tropicamide Combination)
mshdafahwp = niwthkxeqh ewmfcljwtt (pgtftxamoj, aibdccwgfg - bedfmyzqep)
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-
19 Apr 2021
(Aceclidine)
mshdafahwp = lbxwvxljld ewmfcljwtt (pgtftxamoj, bnddcvslac - cerghbzvbs)
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NCT03201562 (Biospace)
ManualManual
Phase 2
Presbyopia
58
Aceclidine+Tropicamide
hbucteexka(gkjoueofpn) = fapshwnoqj rldmevnsab (tlixmwrrqz )
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Positive
30 Jul 2018
Placebo
-
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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