Last update 21 Nov 2024

Hydrochlorothiazide/Triamterene

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Triamterene and Hydrochlorothiazide, 氢氯噻嗪/氨苯蝶啶, Dyazide
+ [2]
Mechanism
NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors), SCNA blockers(Sodium channel alpha subunit blockers)
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (02 Dec 1965),
Regulation-
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Structure

Molecular FormulaC19H19ClN10O4S2
InChIKeyXZRKEDHJXXLVSK-UHFFFAOYSA-N
CAS Registry14124-50-6

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Edema
US
22 Oct 1984
Hypertension
US
22 Oct 1984
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
1
nvyloxlouq(tcucsfdgbx) = A diagnosis of acute nephrogenic diabetes insipidus (NDI) was made vxjhzbeobx (ksslurfzvp )
Positive
05 Nov 2013
Not Applicable
-
(plksueyxlm) = slomtuqyzm xvfalisfbz (sqkpncubeq )
Negative
30 Oct 2012
Hydrochlorothiazide (HCTZ)
(plksueyxlm) = keqglgjlxw xvfalisfbz (sqkpncubeq )
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Regulation

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