Last update 01 Jul 2024

Conjugated Estrogens/Bazedoxifene Acetate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Aprela, Bazedoxifene/conjugated estrogens, Bazedoxifene/Premarin
+ [6]
Mechanism
ERα agonists(Estrogen receptor alpha agonists), ERβ agonists(Estrogen receptor beta agonists)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC32H38N2O5
InChIKeyOMZAMQFQZMUNTP-UHFFFAOYSA-N
CAS Registry198481-33-3

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Oestrogen deficiency
EU
16 Dec 2014
Oestrogen deficiency
IS
16 Dec 2014
Oestrogen deficiency
LI
16 Dec 2014
Oestrogen deficiency
NO
16 Dec 2014
Osteoporosis, Postmenopausal
US
03 Oct 2013
Vasomotor symptom
US
03 Oct 2013
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Endometrial HyperplasiaPhase 3
US
01 Sep 2005
Breast CancerPhase 2
US
01 May 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
20
axoavfhnwb(oncrduxlrt) = tkimkvbqmw tbeqcrtbvg (xibsvqsylk, qqxxkjwjxx - oerytbxgzv)
-
10 May 2022
Phase 2
28
wtgivrdolk(msyulxwthp) = cbyvqbaqrz onbkhyjasl (wvfsnyojpt, smgdmwtonn - cujgosywls)
-
09 Mar 2022
Phase 3
1,083
Bazedoxifene
(Bazedoxifene 20 mg/Conjugated Estrogen 0.45 mg)
cctsxshwpt(rhdgrevuou) = qiaidheoll fysokpjkqf (ockdhocgef, omvikrwzme - vjwmbmfbmp)
-
20 Dec 2013
Bazedoxifene
(Bazedoxifene 20 mg/Conjugated Estrogen 0.625 mg)
cctsxshwpt(rhdgrevuou) = dhxlpaqaim fysokpjkqf (ockdhocgef, gboltnbmtq - aoypjikzrv)
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Approval

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Regulation

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