Last update 21 Nov 2024

Conjugated Estrogens/Bazedoxifene Acetate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Aprela, BZA/CE, Bazedoxifene/Premarin
+ [6]
Mechanism
ERα agonists(Estrogen receptor alpha agonists), ERβ agonists(Estrogen receptor beta agonists)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC32H38N2O5
InChIKeyOMZAMQFQZMUNTP-UHFFFAOYSA-N
CAS Registry198481-33-3

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
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IndicationCountry/LocationOrganizationDate
Oestrogen deficiency
NO
16 Dec 2014
Oestrogen deficiency
LI
16 Dec 2014
Oestrogen deficiency
IS
16 Dec 2014
Oestrogen deficiency
EU
16 Dec 2014
Osteoporosis, Postmenopausal
US
03 Oct 2013
Vasomotor symptom
US
03 Oct 2013
Developing
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IndicationHighest PhaseCountry/LocationOrganizationDate
Breast CancerDiscovery
US
01 May 2016
Endometrial HyperplasiaDiscovery
US
01 Sep 2005
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
20
ixqzapbedi(utnccfrvoh) = wppxnuhzlk pszbyphkbf (hgwrfjtgnu, bspgibbwca - bazahlgwvx)
-
10 May 2022
Phase 2
28
wpcaahsxvm(iiibvdfxwy) = niktchfawc qocrmwzfgj (lyhydaauqm, chgtjqrlue - rgbywkuqyg)
-
09 Mar 2022
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Regulation

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