Last update 01 Nov 2024

Artemether

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(1R,4S,5R,8S,9R,10S,12R,13R)-10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0^{4,13}.0^{8,13}]hexadecane, 10-methoxy-1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecane, Artemether (JAN/USAN/INN)
+ [16]
Mechanism
ATP2A1 inhibitors(Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 inhibitors), SERCA2 inhibitors(Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 inhibitors)
Drug Highest PhaseApproved
First Approval Date
CN (01 Jan 1990),
Regulation-
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Structure

Molecular FormulaC16H26O5
InChIKeySXYIRMFQILZOAM-HVNFFKDJSA-N
CAS Registry71963-77-4

External Link

KEGGWikiATCDrug Bank
D02483Artemether

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Malaria
CN
01 Jan 1990
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Malaria, FalciparumPhase 2
BF
01 Dec 2010
Polycystic Ovary SyndromePreclinical
CN
13 Jun 2024
Advanced Malignant Solid NeoplasmDiscovery
GB
01 Oct 2014
Malaria, FalciparumDiscovery
RW
01 Dec 2010
Malaria, FalciparumDiscovery
GH
01 Dec 2010
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
gbrxvpmvxa(alrpafpwnr) = zymfjnmuka zzwholktfi (vgjarjdkcg )
-
01 Nov 2015
gbrxvpmvxa(alrpafpwnr) = yqjhliljvv zzwholktfi (vgjarjdkcg )
Phase 3
151
hopqhqkwvc(hmytozviwf) = xznynprnbk duseffignc (bgbfhykbhf, bluzpxkodo - pjoyqzpehq)
-
28 Feb 2014
(Quinine)
hopqhqkwvc(hmytozviwf) = mugyiciskb duseffignc (bgbfhykbhf, wmnvrcepkv - ymzpwdyzng)
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Approval

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Regulation

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