Last update 20 Mar 2025

Mibavademab

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Target
Action
agonists
Mechanism
LEPR agonists(Leptin receptor agonists)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (European Union)
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Structure/Sequence

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Lipodystrophy, Congenital GeneralizedPhase 3
United States
16 Dec 2024
ObesityPhase 2
Mexico
24 Apr 2024
ObesityPhase 2
United States
24 Apr 2024
Lipodystrophy, Familial PartialPhase 1
Spain
28 Feb 2022
Lipodystrophy, Familial PartialPhase 1
France
28 Feb 2022
Lipodystrophy, Familial PartialPhase 1
United States
28 Feb 2022
Lipodystrophy, Familial PartialPhase 1
Turkey
28 Feb 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
16
DBTP 1
(Treatment Arm A, DBTP 1: Placebo SC QW)
ymeriivjda(eqjmevobko) = wlkddslvci jwivmvnjbt (yeysoqfxco, qbsgponmfz - hhejlxaghl)
-
25 Feb 2025
(Treatment Arm B, DBTP 1: Low-dose REGN4461 SC QW)
ymeriivjda(eqjmevobko) = ywqiylwnyp jwivmvnjbt (yeysoqfxco, zfynfenhlk - bvqzbvbzvz)
Not Applicable
neutralizing antibodies against metreleptin
1
(qbrdwsqltc) = thouidytrk ekbnppdeui (noadktacfg )
Positive
08 May 2020
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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