Last update 22 Dec 2024

Benzocaine/Tetracaine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Tetracaine/benzocaine, CTY-5339, CTY-5339-A
+ [1]
Target
Nav1.8 x RYR1 x RYR2
Mechanism
Nav1.8 blockers(Sodium channel protein type X alpha subunit blockers), RYR1 modulators(Ryanodine receptor 1 modulators), RYR2 modulators(Ryanodine receptor 2 modulators)
Therapeutic Areas
Other Diseases
Active Indication
Anesthesia
Inactive Indication
Pain
Originator Organization
Cetylite Industries, Inc.Cetylite Industries, Inc.
Active Organization
University of Pennsylvania School of Dental MedicineUniversity of Pennsylvania School of Dental Medicine
Inactive Organization
Cetylite Industries, Inc.Cetylite Industries, Inc.
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC9H11NO2
InChIKeyBLFLLBZGZJTVJG-UHFFFAOYSA-N
CAS Registry94-09-7
View All Structures (2)

Related

2
Clinical Trials associated with Benzocaine/Tetracaine
NCT03233737 / CompletedPhase 2
A Double-blind, Cross-over, Incomplete Factorial Study to Assess the Local Anesthetic Efficacy and Safety of CTY-5339 Anesthetic Spray (CTY-5339A) When Applied to the Gingival Mucosal Tissue in Normal Volunteers
NCT02908620 / CompletedPhase 2
A Double-blind, Partial Cross-over, Incomplete Factorial Study to Assess the Local Anesthetic Efficacy and Safety of CTY-5339 Anesthetic Spray (CTY-5339-A) When Applied to the Cheek Mucosal Tissue in Normal Volunteers
100 Clinical Results associated with Benzocaine/Tetracaine
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100 Translational Medicine associated with Benzocaine/Tetracaine
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100 Patents (Medical) associated with Benzocaine/Tetracaine
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100 Deals associated with Benzocaine/Tetracaine
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
AnesthesiaPhase 2
US
Cetylite Industries, Inc.Cetylite Industries, Inc.
07 Dec 2016
PainPhase 2
US
Cetylite Industries, Inc.Cetylite Industries, Inc.
07 Dec 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03233737 (CTgov)
Phase 2
Pain
75
(Stage I: One Spray CTY-5339-A)
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-
21 Aug 2019
One spray CTY-5339-CB
(Stage I: One Spray CTY-5339-CB)
gcbvtslbfy(syygxpaydd) = smrfyjmqmq qohqvytkjl (qslimrirvn, jusnmwcejo - oecvxdvzht)
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Approval

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Regulation

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