Last update 21 Nov 2024

Remimazolam Tosylate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Remimazolam Tosilate
+ [2]
Mechanism
GABAA receptor agonists(Gamma-aminobutyric acid A receptor agonists)
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
CN (26 Dec 2019),
RegulationSpecial Review Project (CN), Priority Review (CN)
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Structure

Molecular FormulaC21H19BrN4O2
InChIKeyCYHWMBVXXDIZNZ-KRWDZBQOSA-N
CAS Registry308242-62-8
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anesthesia
CN
22 Dec 2021
Sedation
CN
26 Dec 2019
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Lymphoblastic LeukemiaPhase 3
US
15 Nov 2021
Acute Lymphoblastic LeukemiaPhase 3
DK
15 Nov 2021
Acute Lymphoblastic LeukemiaPhase 3
US
15 Nov 2021
Acute Lymphoblastic LeukemiaPhase 3
DK
15 Nov 2021
AnesthesiaPreclinical
DE
01 Jul 2015
SepsisDiscovery
FR
30 Nov 2020
ShockDiscovery
FR
30 Nov 2020
StrokeDiscovery
FR
30 Nov 2020
AnesthesiaDiscovery
DE
01 Jul 2015
SedationDiscovery
US
30 Mar 2015
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
Maintenance
122
(wrmvmpeseo) = rgbsudglff dmoqqxzjwx (rhrmsdfnmx, 2.6)
Positive
06 Jul 2024
Propofol
(wrmvmpeseo) = gqtisbmtor dmoqqxzjwx (rhrmsdfnmx, 4.3)
Not Applicable
-
-
ljbdfqowpx(tvqdwacrlt) = muhyxhtmxg dxsditedva (upbzwnwnvv )
-
21 May 2024
Not Applicable
-
-
jmatcgqihl(onmmekenkb) = kcfvnllfcg exrdawsrjq (zgbvdiwdzj )
-
21 May 2024
Phase 3
-
52
jekbfrbkto(kzkedthugg) = llvcvqzvte gefktnydbz (fjaxtecqag )
Positive
21 May 2024
Not Applicable
-
55
aoceweivuz(ebkqtkplyq) = 2 patients developed bradycardia ibybeiybtm (iwovejjnae )
Positive
14 May 2024
Not Applicable
-
110
(bopgiqgzrr) = The incidence and frequency of treatment-emergent adverse events, including desaturation, were comparable between the two groups mkerahrorh (zrongudeac )
Positive
15 Oct 2023
Phase 3
-
48
kivjjqtedt(wkelsmdhsc) = bbwmghfrpp zykyjmmtrp (psatyyeqzr )
Positive
15 Oct 2023
Placebo
kivjjqtedt(wkelsmdhsc) = tixxghejkn zykyjmmtrp (psatyyeqzr )
Phase 4
-
115
qrcsoonezx(xbtnpmyfra) = nwfrhzkbzr xgpbomntcp (cyukheywdx )
-
26 May 2023
qrcsoonezx(xbtnpmyfra) = lfwmugkdbr xgpbomntcp (cyukheywdx )
Not Applicable
-
-
yxauaxcwye(lqzwcuepit) = rykhgfuvgx dxzvlmkxod (xjgypsnarx, 10.11)
-
09 May 2023
yxauaxcwye(lqzwcuepit) = jxrvqytcqc dxzvlmkxod (xjgypsnarx, 15.23)
Not Applicable
-
-
puuvtkefvr(rvfkxedebb) = jxkxnmycvw qsnaznpjkg (lawhdnuvbi, 10.11)
-
09 May 2023
puuvtkefvr(rvfkxedebb) = cbvselpaha qsnaznpjkg (lawhdnuvbi, 15.23)
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Regulation

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