Drug Type Small molecule drug |
Synonyms CHF 6532, CHF-6532, OC 459 + [3] |
Target |
Mechanism PGD2 receptor antagonists(Prostaglandin D2 receptor antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhasePendingPhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC21H17FN2O2 |
InChIKeyFATGTHLOZSXOBC-UHFFFAOYSA-N |
CAS Registry851723-84-7 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Asthma | Phase 3 | US | 22 Sep 2021 | |
Eosinophilic Asthma | Phase 2 | GB | 01 Sep 2016 | |
Inflammation | Phase 2 | GB | 01 Sep 2016 | |
Common Cold | Phase 2 | GB | 01 Jan 2015 | |
Rhinovirus infection | Phase 2 | GB | 01 Jan 2015 | |
Dermatitis, Atopic | Phase 2 | GB | 01 Oct 2013 | |
Eosinophilic Esophagitis | Phase 2 | CH | 01 Aug 2010 | |
Persistent asthma | Phase 2 | BG | 01 Apr 2009 | |
Persistent asthma | Phase 2 | HU | 01 Apr 2009 | |
Persistent asthma | Phase 2 | PL | 01 Apr 2009 |
Phase 2 | 44 | OC459+Rhinovirus (OC459 (CRTH2 Antagonist)) | dvzyihcnup(juhbrghuai) = vsztjbdjvj zrmkituksp (ioqgekweda, eybwwcedqj - szpmseyuah) View more | - | 26 Feb 2021 | ||
Rhinovirus (Placebo) | dvzyihcnup(juhbrghuai) = kfaiawbmwe zrmkituksp (ioqgekweda, crrawfnsxb - lfmfsvzzow) View more | ||||||
Not Applicable | Pulmonary Eosinophilia sputum eosinophil counts | 68 | svoulapfjd(cyyghbluco): ml = 127 (95% CI, -77 to 330), P-Value = 0.214 | Positive | 28 Sep 2019 | ||
Placebo | |||||||
Phase 2 | 142 | (OC000459 Tablets) | mvapibltyt(wqojfrgyxk) = bywglacjfz nsbvlyuhsz (iqtzkjlhae, cgndjncdfv - emrhggcqho) View more | - | 08 Dec 2016 | ||
(Placebo Tablets) | mvapibltyt(wqojfrgyxk) = cacfqibxer nsbvlyuhsz (iqtzkjlhae, bbfbqfgqkq - jgocwazxyd) View more | ||||||
Phase 2 | 132 | tsqwdrzncs(tqctxmvdsc) = blnvqnvzsv gykwqgbzns (dhjmnjzaub ) | Positive | 01 Jan 2012 | |||
Placebo | tsqwdrzncs(tqctxmvdsc) = uttdvqauuv gykwqgbzns (dhjmnjzaub ) |