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Last update 08 May 2025
Zibotentan/Dapagliflozin
Last update 08 May 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms- |
Target |
Action antagonists, inhibitors |
Mechanism ETA antagonists(Endothelin receptor type A antagonists), SGLT2 inhibitors(Sodium/glucose cotransporter 2 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 3 |
First Approval Date- |
Regulation- |
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Structure/Sequence
Molecular FormulaC19H16N6O4S |
InChIKeyFJHHZXWJVIEFGJ-UHFFFAOYSA-N |
CAS Registry186497-07-4 |
View All Structures (2)
Related
5
Clinical Trials associated with Zibotentan/DapagliflozinNCT06942910
A Multicentre, Randomised, Double-blind, Active-Controlled, 2-arm Parallel-group Treatment, Phase II Study to Evaluate the Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin Alone in Adult Participants With Chronic Kidney Disease and High Proteinuria
CTR20241892
一项在慢性肾脏病和高蛋白尿受试者中评价Zibotentan/达格列净与达格列净单药治疗相比的有效性、安全性和耐受性的 III期、随机、多中心、双盲研究
[Translation] A Phase III, randomized, multicenter, double-blind study to evaluate the efficacy, safety, and tolerability of Zibotentan/dapagliflozin compared with dapagliflozin monotherapy in subjects with chronic kidney disease and hyperalbuminuria
NCT06269484
A Multicentre, Randomised, Double-blind, Placebo-controlled Study to Evaluate the Safety of Zibotentan/Dapagliflozin in Combination Compared to Zibotentan Monotherapy, Zibotentan/Dapagliflozin and Zibotentan Monotherapy Compared to Placebo in Participants With Cirrhosis
100 Clinical Results associated with Zibotentan/Dapagliflozin
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100 Translational Medicine associated with Zibotentan/Dapagliflozin
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100 Patents (Medical) associated with Zibotentan/Dapagliflozin
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100 Deals associated with Zibotentan/Dapagliflozin
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Proteinuria | Phase 3 | Spain | 07 Nov 2023 | |
| Proteinuria | Phase 3 | Germany | 07 Nov 2023 | |
| Proteinuria | Phase 3 | Japan | 07 Nov 2023 | |
| Proteinuria | Phase 3 | Vietnam | 07 Nov 2023 | |
| Proteinuria | Phase 3 | South Korea | 07 Nov 2023 | |
| Proteinuria | Phase 3 | Poland | 07 Nov 2023 | |
| Proteinuria | Phase 3 | Canada | 07 Nov 2023 | |
| Proteinuria | Phase 3 | Netherlands | 07 Nov 2023 | |
| Proteinuria | Phase 3 | Turkey | 07 Nov 2023 | |
| Proteinuria | Phase 3 | Malaysia | 07 Nov 2023 |
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