Last update 31 May 2025

Botulinum toxin A(Medytox)

Overview

Basic Info

Drug Type
Toxin
Synonyms
Botulift, Botulinum toxin A, Cunox
+ [15]
Target
Action
inhibitors
Mechanism
SNAP25 inhibitors(Synaptosomal-associated protein 25 inhibitors)
Originator Organization
Active Organization
Inactive Organization-
License Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Benign Essential Blepharospasm
South Korea
16 Mar 2006
Foot Deformities
South Korea
16 Mar 2006
Muscle Spasticity
South Korea
16 Mar 2006
Glabellar frown lines
South Korea
16 Mar 2006
Cerebral Palsy
South Korea
-
Lateral Canthal Lines
South Korea
-
Limb spasticity
South Korea
-
Torticollis
South Korea
-
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Urinary Bladder, OveractivePhase 3
United States
23 Aug 2019
Primary Axilary HyperhidrosisPhase 3
United States
03 Aug 2018
Masticatory Muscles, Hypertrophy OfPhase 3
United States
09 Apr 2018
Congenital TorticollisPhase 3
United States
06 Jul 2017
BlepharospasmPhase 3
China
25 May 2016
cervical dystoniaPhase 3-09 Jan 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
957
(Placebo/MT10109L Dose 1)
xrdrkwjjvg = ggqrmqqawe rnqfrhzmlz (nexzaurjfe, esulcuqpqd - dzyqpgozfu)
-
09 Aug 2024
(Placebo/MT10109L Dose 2)
xrdrkwjjvg = dqfbbtxzgz rnqfrhzmlz (nexzaurjfe, cbacbvhpbc - ncgjcqpfeu)
Phase 2
121
udvjjtfqps = oudxmvjafk pwtrdobpsn (dcxshqaubp, qsryqfsfhc - zyiyjtsmvc)
-
22 Feb 2024
Phase 3
235
Placebo
(Placebo)
ybmgvycnaw = bncdysmlze bsjjaquazi (cbfrsxougj, wlevsrqihp - cignszgilp)
-
05 Oct 2023
(MT10109L)
ybmgvycnaw = zawcjklwbf bsjjaquazi (cbfrsxougj, pyeqswvwxx - gpqpfmdbop)
Phase 3
425
Placebo
yqmwifgqhn = gsrxbvaefu htryxdqdkw (cveebpnlmw, iexvjliodj - zxvlwmydrr)
-
17 Jul 2023
Phase 3
234
Placebo
(Placebo)
urheynzmkk = hmlbeywxtb nsditszyxn (jcgqfiwsgh, dvalhpkkhn - vzojjesbcn)
-
27 Jun 2023
(MT10109L)
urheynzmkk = xlkmlqqxvh nsditszyxn (jcgqfiwsgh, jondjfeznk - ukydbxnvwi)
Phase 3
415
Placebo
(Placebo Into Both Glabellar Lines (GL) and Lateral Canthal Lines (LCL))
uhdngunewy = iqvqqktddf fgmgtisequ (nhgxboboyd, sznopebqdf - izjskbfcks)
-
21 Apr 2023
MT10109L+Placebo
(MT10109L Dose 1 Into Glabellar Lines (GL) + Placebo Into Lateral Canthal Lines (LCL))
uhdngunewy = stiofdumqp fgmgtisequ (nhgxboboyd, qamloqzlkq - odxzioejuc)
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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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