Drug Type Small molecule drug |
Synonyms IOWH 032, IOWH032 |
Target |
Action inhibitors |
Mechanism CFTR inhibitors(Cystic fibrosis transmembrane conductance regulator inhibitors) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC22H15Br2N3O4 |
InChIKeyDSFNLJXHXBIKDS-UHFFFAOYSA-N |
CAS Registry1191252-49-9 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acute diarrhea | Phase 2 | Bangladesh | 01 Jun 2014 | |
Cholera | Phase 2 | Bangladesh | 01 Jun 2014 | |
Secretory diarrhea | Phase 2 | Bangladesh | 01 Jun 2014 | |
Diarrhea | Phase 1 | United States | - |
Phase 2 | 47 | dnwjeemjqx(dtgkfowkdx) = iomsblamit letgxaxvtx (jmxlvyumyn, 8.9 - 58.3) | Negative | 18 Nov 2021 | |||
Placebo | dnwjeemjqx(dtgkfowkdx) = nzszbrycxw letgxaxvtx (jmxlvyumyn, 15.8 - 48.2) | ||||||
Phase 2 | 47 | Antibiotics+iOWH032 (iOWH032) | mctwehcppf(onphqzciek) = lhmohlmlgs cdckkaxlww (ucwmpbnacm, wemosuykts - zemaobskbk) View more | - | 25 Mar 2021 | ||
Placebo (Placebo) | mctwehcppf(onphqzciek) = mgdurxtwzy cdckkaxlww (ucwmpbnacm, fgghqgdumu - bcgowlpbzh) View more |