Last update 13 Dec 2025

RJ4287

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
RJ 4287, RJ4287
Target
THR
Action
modulators
Mechanism
THR modulators(Thyroid hormone receptor modulators)
Therapeutic Areas
Digestive System Disorders
Active Indication
Metabolic Dysfunction Associated Steatohepatitis
Inactive Indication-
Originator Organization
Nanjing Ruijie Pharma Co., Ltd.Nanjing Ruijie Pharma Co., Ltd.
Active Organization
Orimos Therapeutics Co., Ltd.
Inactive Organization
Nanjing Ruijie Pharma Co., Ltd.Nanjing Ruijie Pharma Co., Ltd.
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with RJ4287
NCT05921006
/ Unknown statusPhase 1
A Phase 1, Double-blind, Randomized, Placebo-controlled, First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Food-effect of Single and Multiple Oral Doses of RJ4287 in Healthy Volunteers
CTR20254632
/ Not yet recruitingPhase 2
评价RJ4287片在代谢相关脂肪性肝炎（MASH）成人患者中的安全性、耐受性、初步有效性和药代动力学特征的多中心、随机、安慰剂对照的Ⅱa期临床研究
[Translation] A multicenter, randomized, placebo-controlled phase IIa clinical trial evaluating the safety, tolerability, preliminary efficacy, and pharmacokinetic characteristics of RJ4287 tablets in adult patients with metabolic-associated steatohepatitis (MASH).
100 Clinical Results associated with RJ4287
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100 Translational Medicine associated with RJ4287
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100 Patents (Medical) associated with RJ4287
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100 Deals associated with RJ4287
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metabolic Dysfunction Associated SteatohepatitisPhase 2
China
Orimos Therapeutics Co., Ltd.
01 Dec 2025
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Clinical Result

Indication
Phase
Evaluation
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Phase
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Core Patent

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Clinical Trial

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Approval

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Regulation

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