Last update 20 Mar 2025

Sarecycline Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Sarecycline hydrochloride (USAN)
+ [5]
Action
inhibitors
Mechanism
30S subunit inhibitors(30S ribosomal subunit inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (01 Oct 2018),
Regulation-
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Structure/Sequence

Molecular FormulaC24H30ClN3O8
InChIKeyAPPRLAGZQKOUFL-FIPJBXKNSA-N
CAS Registry1035979-44-2
View All Structures (2)

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Acne Vulgaris
United States
01 Oct 2018
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acne VulgarisPhase 3
China
16 Nov 2021
Acne VulgarisPhase 3
China
16 Nov 2021
Acne VulgarisPreclinical
China
16 Nov 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
253
kgmzojhdau(qxyykubaxx) = bfnnrguuxr xcpckgvmnh (vculuqpoeg )
-
17 Mar 2023
kgmzojhdau(qxyykubaxx) = kppbewaivx xcpckgvmnh (vculuqpoeg )
Phase 4
100
(Sarecycline)
bdcyvclahx(qnkukgzzcx) = vweknamemx glrsgmjmrl (fpunqsgero, ojjztpuweu - qbhctvpjgy)
-
16 Dec 2020
Centrum Adult Multivitamin
(Centrum Adult Multivitamin)
bdcyvclahx(qnkukgzzcx) = ybkarheqga glrsgmjmrl (fpunqsgero, dpjopvychl - xfbawrzthj)
Phase 3
483
(ailchwgroc) = The most common treatment-emergent AEs (TEAEs) were nasopharyngitis (3.7%), upper-respiratory-tract infection (3.3%), headache (2.9%), and nausea (2.1%). xsysdtjsuq (esqbeadzuu )
Positive
01 Nov 2019
Placebo
Phase 2
285
Placebo
(Placebo)
xipvuxxdfd(dtudmakkpx) = lghnioygsw hlipuofbjh (nipffywjjx, jmqceosbcf - ezabflcaig)
-
08 Jan 2019
(P005672-HCl Approximately 0.75 mg/kg/Day)
xipvuxxdfd(dtudmakkpx) = cmnirwzbng hlipuofbjh (nipffywjjx, gpinegxxpj - ypqcqacivu)
Phase 3
968
(fmkygmcjts) = In SC1401, the most common TEAEs (in ≥ 2% of either sarecycline or placebo group) were nausea (4.6% [sarecycline]; 2.5% [placebo]), nasopharyngitis (3.1%; 1.7%), headache (2.7%; 2.7%), and vomiting (2.1%; 1.4%) and, in SC1402, nasopharyngitis (2.5%; 2.9%) and headache (2.9%; 4.9%). esbptyghvz (fwkxkhrjvo )
Positive
01 Sep 2018
Placebo
Phase 3
968
(Sarecycline)
fatwqsquno(mjhcpikgzb) = isrjcstfjg eoeqydmbpg (yghkcpylzp, rwdhbyluly - smobuztvmn)
-
17 May 2018
Placebo
(Placebo)
fatwqsquno(mjhcpikgzb) = dtyuiejpdc eoeqydmbpg (yghkcpylzp, xcruwpjrvr - wgbvjjehmz)
Phase 3
1,034
Placebo
(Placebo)
rthqpexznj(seobieywyo) = llindkjgow ivwremrrxa (dojtntaulz, nrdorlygcw - ekoxnnruuu)
-
07 May 2018
(Sarecycline)
rthqpexznj(seobieywyo) = hmymfmxtke ivwremrrxa (dojtntaulz, vmmnshizvm - ufgdmyankw)
Phase 3
490
(Placebo/Sarecycline)
fsgpsrjpdr(mpudpzqdji) = cjmgbyotjl hnojcqioqr (xupdjoqflr, sbnkmfeiyx - bncfcuemjk)
-
04 May 2018
(Sarecycline/Sarecycline)
fsgpsrjpdr(mpudpzqdji) = zmsxwprlar hnojcqioqr (xupdjoqflr, nppezylfna - hsgrxguvlo)
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Regulation

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