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Last update 20 Jul 2025
BI-443651
Last update 20 Jul 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms BI 443651, BI443651 |
Target |
Action blockers |
Mechanism ENaC blockers(Epithelial sodium channel blockers) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhasePendingPhase 1 |
First Approval Date- |
Regulation- |
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Related
3
Clinical Trials associated with BI-443651NCT03135899
A Two Part Phase I, Multiple-dose, Single- and Double-blind, Randomised, Double-dummy, Placebo-controlled, Four-way Crossover Study to Assess Safety and Tolerability of BI 443651 Via Respimat® Versus Placebo Via Respimat® in Subjects With Mild Asthma Following Methacholine Challenge.
NCT02976519
A Phase Ib, Multicentre, Double Blind, Randomized, Two-part Study, First Part Multiple Rising Dose and Second Part Two-way Cross-over, to Assess Safety, Tolerability, Efficacy and Pharmacokinetics of BI 443651 Compared to Placebo Via Respimat® in Healthy Volunteers and CF Subjects.
NCT02706925
Safety, Tolerability and Pharmacokinetics of Single Rising Inhaled Doses of BI 443651 in Healthy Male Volunteers in a Partially Randomised, Single Blind, Placebo-controlled Trial
100 Clinical Results associated with BI-443651
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100 Translational Medicine associated with BI-443651
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100 Patents (Medical) associated with BI-443651
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100 Deals associated with BI-443651
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Asthma | Phase 1 | United Kingdom | 18 May 2017 | |
| Cystic Fibrosis | Phase 1 | Germany | 15 Feb 2017 | |
| Cystic Fibrosis | Phase 1 | United Kingdom | 15 Feb 2017 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
Phase 1 | - | 63 | Placebo | loyfunbszy = xhzlmiduwc aigpjtsuvj (zyzatdiubp, vokyyuqtnx - ytupjatlwu) View more | - | 02 Jan 2020 | |
Phase 1 | 64 | (Placebo Matching BI 443651) | oepyjsmzin = eefkohpalh agzrznvyjq (maeaedbstf, nhdhujkpjz - ilunffdsnw) View more | - | 27 Nov 2019 | ||
(BI 443651 100 Microgram (μg)) | oepyjsmzin = xsxceendut agzrznvyjq (maeaedbstf, jikpidnioe - qfeaygxhju) View more |
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