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Last update 20 Mar 2025
ThisCART 19(Fundamenta Therapeutics,)
Last update 20 Mar 2025
Overview
Basic Info
Drug Type Universal CAR-T |
Synonyms THISCART-19 |
Target |
Action inhibitors |
Mechanism CD19 inhibitors(B-lymphocyte antigen CD19 inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
Regulation- |
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Related
7
Clinical Trials associated with ThisCART 19(Fundamenta Therapeutics,)NCT05776407
A Single Dose-escalation and Dose-expansion Study to Evaluate the Safety, Efficacy and Pharmacokinetics of Allogeneic CAR-T Targeting CD19 in Patients With Refractory or Relapsed B Cell Lymphoma.
NCT05640713
A Single Dose-escalation Study to Evaluate the Safety and Efficacy of Allogeneic CAR-T Targeting CD19 (ThisCART19A) in Adult Patients With B Cell Malignancies After Failure of Autologous Chimeric Antigen Receptor T- Cell(CAR-T) Therapy
NCT05691153
A Single-center, Dose Selection Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Allogeneic CAR-T Targeting CD19 in Patients With Auto-CAR T Relapsed B-cell Non-Hodgkin's Lymphoma
100 Clinical Results associated with ThisCART 19(Fundamenta Therapeutics,)
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100 Translational Medicine associated with ThisCART 19(Fundamenta Therapeutics,)
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100 Patents (Medical) associated with ThisCART 19(Fundamenta Therapeutics,)
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100 Deals associated with ThisCART 19(Fundamenta Therapeutics,)
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| AIDS-Related Lymphoma | Phase 2 | China | 01 May 2023 | |
| CD19 positive B-Cell Lymphoma | Phase 2 | China | 01 May 2023 | |
| B-cell lymphoma recurrent | Phase 1 | China | 01 Dec 2022 | |
| Pre B-cell acute lymphoblastic leukemia | Phase 1 | China | 01 Dec 2022 | |
| Recurrent Non-Hodgkin Lymphoma | Phase 1 | China | 01 Dec 2022 | |
| Refractory Adult Acute Lymphoblastic Leukemia | Phase 1 | China | 01 Dec 2022 | |
| Refractory B Acute Lymphoblastic Leukemia | Phase 1 | - | 15 Oct 2022 | |
| B-Cell Malignant Neoplasm | Phase 1 | China | 25 Oct 2021 | |
| B-cell lymphoma refractory | Discovery | China | 25 Oct 2021 | |
| B-Cell Leukemia | Discovery | China | 09 May 2020 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
View All Results
NCT04384393 (ASGCT2024) Manual  | Phase 1 | 2 | (gfacppuflo) = not observed oywdabkyzw (kbmreqdpqw ) View more | Positive | 07 May 2024 | ||
NCT04384393 (EHA2022) Manual | Phase 1 | CD19 positive Non-Hodgkin Lymphoma CD19 Positive | 8 | Fludarabine Phosphate+Cyclophosphamide+ThisCART 19 | (fsbqfvamiw) = awozgndjjo moztkvuusd (lpbetydkll ) View more | Positive | 12 May 2022 |
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