Last update 12 Feb 2026

GKL-006

Overview

Basic Info

Drug Type
iNKT cell therapy, CAR-NKT
Synonyms
GKL 006, GKL-006, GKL006
Target
GPC3
Action
inhibitors
Mechanism
GPC3 inhibitors(Glypican-3 inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease+ [2]
Active Indication
Unresectable Hepatocellular CarcinomaPancreatic CancerPsoriasis
Inactive Indication-
Originator Organization
Beijing Gene Key Life Technology Co., LtdBeijing Gene Key Life Technology Co., Ltd
Active Organization
Beijing Gene Key Life Technology Co., LtdBeijing Gene Key Life Technology Co., Ltd
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

5
Clinical Trials associated with GKL-006
CTR20253777
/ RecruitingPhase 2
GKL-006注射液联合经动脉化疗栓塞（TACE）对比单纯TACE治疗不可切除的肝细胞癌的多中心、随机、开放、对照的II期临床试验
[Translation] A multicenter, randomized, open-label, controlled phase II clinical trial of GKL-006 injection combined with transarterial chemoembolization (TACE) versus TACE alone in the treatment of unresectable hepatocellular carcinoma
NCT07209813
/ Not yet recruitingPhase 2
A Phase Ⅱ, Multicenter, Parallel Comparison Clinical Study of GKL-006 Combined With TACE in Treatment of Unresectable Hepatocellular Carcinoma
CTR20252552
/ RecruitingPhase 1/2
评价GKL-006注射液治疗晚期胰腺癌患者的安全性、耐受性、药代动力学特征和初步疗效的Ⅰ/Ⅱa期临床试验
[Translation] Phase I/IIa clinical trial to evaluate the safety, tolerability, pharmacokinetic characteristics and preliminary efficacy of GKL-006 injection in the treatment of patients with advanced pancreatic cancer
100 Clinical Results associated with GKL-006
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100 Translational Medicine associated with GKL-006
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100 Patents (Medical) associated with GKL-006
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100 Deals associated with GKL-006
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Unresectable Hepatocellular CarcinomaPhase 2
China
Beijing Gene Key Life Technology Co., LtdBeijing Gene Key Life Technology Co., Ltd
10 Sep 2025
Pancreatic CancerPhase 2
China
Beijing Gene Key Life Technology Co., LtdBeijing Gene Key Life Technology Co., Ltd
04 Aug 2025
PsoriasisIND Approval
China
Beijing Gene Key Life Technology Co., LtdBeijing Gene Key Life Technology Co., Ltd
12 Feb 2026
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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