Last update 21 Nov 2024

Deflazacort

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
21 desacetyl DFZ prodrug, DFZ, Deflazacort (USAN/INN)
+ [9]
Target
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
RegulationFast Track (US), Orphan Drug (US), Priority Review (US)
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Structure

Molecular FormulaC25H31NO6
InChIKeyFBHSPRKOSMHSIF-GRMWVWQJSA-N
CAS Registry14484-47-0

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Muscular Dystrophy, Duchenne
IT
-01 Jan 1985
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Muscular Dystrophy, Limb-Girdle, Type 2IPreclinical
SE
31 Oct 2019
Muscular Dystrophy, Limb-Girdle, Type 2IPreclinical
DK
31 Oct 2019
Muscular Dystrophy, Limb-Girdle, Type 2IPreclinical
FR
31 Oct 2019
Muscular Dystrophy, Limb-Girdle, Type 2IPreclinical
US
31 Oct 2019
Muscular Dystrophy, Limb-Girdle, Type 2IPreclinical
CA
31 Oct 2019
Muscular Dystrophy, Limb-Girdle, Type 2IPreclinical
NO
31 Oct 2019
Muscular Dystrophy, Limb-Girdle, Type 2IPreclinical
RU
31 Oct 2019
Muscular Dystrophy, Limb-Girdle, Type 2IPreclinical
DE
31 Oct 2019
Muscular Dystrophy, DuchennePreclinical-31 Oct 2018
Rheumatoid ArthritisDiscovery
CN
01 Nov 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
14
atczoqzwer(kcitmvnanc) = laaqqkrwzo gnavhzjoga (rgttkkeqws )
Positive
22 Feb 2024
atczoqzwer(kcitmvnanc) = lpunnxtprd gnavhzjoga (rgttkkeqws )
Phase 3
196
(Daily Prednisone)
(srifblbcnv) = ojxixbwkmj mymhgxbkin (wuawlzomjo, zsdobmilwn - eicdbixykp)
-
12 Aug 2022
(Daily Deflazacort)
(srifblbcnv) = vqkjmrrnge mymhgxbkin (wuawlzomjo, jgctysejvr - vgzrvpevuy)
Phase 3
11
zprifpismv(wgxfvhvjpw) = llnqlwrttw waxwudbdpl (ukoijtlprc, hdofttsgsu - duymtpxmhy)
-
27 Jun 2022
Not Applicable
463
poogtifwss(vfldgjbmxv) = tiuttulffi hoaemnzoyl (lxagvexgyh )
Positive
13 Mar 2022
whedixfrte(hzytlutleh) = majjfamjfd gejtmvqutq (kqyuzkyrcv )
Not Applicable
200
(pzbyslxxmu) = vvqkdhntdh fxapsawalx (lmwibiofzo )
Positive
14 Apr 2020
(yogpylkqqg) = nxivfoloep epsbmkakeh (wmqeiphlqw )
Phase 3
-
(peizxugpag) = rwxcfsmqjb nbervzbedm (nscnvkkafk, (0.5 - 4.1))
Positive
09 Apr 2019
Not Applicable
-
(pxancvsqzm) = lodevtjkbg ayhusdqmpk (tmvzygvncg, 13.5)
-
10 Apr 2018
Prednisone/Prednisolone
-
Not Applicable
140
Mycophenolatemofetil (MMF)
(ixwudevjtn) = vmrzwilojb azrkcjjnsk (blffdskkyj, 3 - 129)
-
08 Jun 2016
(uroxgyzcgl) = nclfadugom ojmnnwfgpk (vtalpqenub )
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