Last update 21 Nov 2024

Mosedipimod

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Mosedipimod (USAN/INN), PLAG
Target
Mechanism
CD4 agonists(T-cell surface antigen CD4 agonists), CD8 stimulants(Cluster of differentiation 8 stimulants)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
RegulationFast Track (US), Breakthrough Therapy (US), Orphan Drug (US)
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Structure

Molecular FormulaC39H70O6
InChIKeyGAKUNXBDVGLOFS-DUZKARGPSA-N
CAS Registry221139-79-3

External Link

KEGGWikiATCDrug Bank
D11668--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Moderate Atopic DermatitisPhase 2-01 May 2025
Severe Atopic DermatitisPhase 2-01 May 2025
Respiratory Distress Syndrome, AcutePhase 2
US
30 Apr 2021
COVID-19Phase 2
KR
28 May 2020
Mouth NeoplasmsPhase 2
US
03 Jul 2018
StomatitisPhase 2
US
03 Jul 2018
Advanced breast cancerPhase 2
KR
30 Oct 2017
Advanced cancerPhase 2
KR
30 Oct 2017
Chemotherapy-Induced Febrile NeutropeniaPhase 2
KR
30 Oct 2017
Nonalcoholic SteatohepatitisPhase 1--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
105
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-
02 Jun 2022
gfvxttwmxf(sgsnlbfyha) = puzurlvbds zergyfuyis (haxrgqneid )
Not Applicable
48
(rinkbvhahg) = there was a tendency that the PLAG group was comprised of relatively mild CIN whereas the control group was comprised of those with more severe CIN acuilbuhfm (dhmkzgofzi )
-
20 May 2015
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Regulation

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