Last update 21 Nov 2024

Flecainide Acetate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(±)-flecainide, Flecaine, Flecainide
+ [11]
Target
Mechanism
Nav1.5 blockers(Sodium channel protein type V alpha subunit blockers)
Therapeutic Areas
Active Indication
Originator Organization
Active Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC19H24F6N2O5
InChIKeyRKXNZRPQSOPPRN-UHFFFAOYSA-N
CAS Registry54143-56-5
View All Structures (2)

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Tachycardia
JP
30 Sep 1998
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
54
(qatjvrsrfd) = uyhglpwaqo zfddxvkryw (debauhcjtn )
Negative
30 Sep 2024
Placebo
(qatjvrsrfd) = engceblqhu zfddxvkryw (debauhcjtn )
Not Applicable
-
-
(H558R-/-)
vjtyvqejwk(qluppkkgpl): ARR = -21.5 (95% CI, -38.4 to -4.6), P-Value = 0.02
-
01 Sep 2024
(H558R+/-)
Phase 2
22
(Placebo)
prwtlldxhv(geyvahngfe) = ackozenjrn xaiolidyud (imgswvsgho, thottekaun - jpzihlfwnb)
-
20 Aug 2024
(Flecainide)
prwtlldxhv(geyvahngfe) = lplfackrww xaiolidyud (imgswvsgho, jjmwfairou - amzrvpotbs)
Phase 2
98
yebktxndwe(llduhikzkg) = tqjsusfcfm uzhalrtnqp (qomnuwefqw )
Positive
26 Mar 2024
Not Applicable
81
brerrlkkzd(vqnpwlvspi) = cbkbqlsokj prjlkchfgx (gmuuogoalv, 36 - 70)
-
29 Aug 2022
brerrlkkzd(vqnpwlvspi) = okaenfvdef prjlkchfgx (gmuuogoalv, 29 - 64)
Phase 2
54
(iadwiacuoq) = oyplobbnjt ydmjvrqmsy (ykcndbjipn )
-
29 Aug 2022
(iadwiacuoq) = nwencdkhxa ydmjvrqmsy (ykcndbjipn )
Phase 2
101
(huosyrmocp) = cough 41%;throat pain 14%;throat irritation 3% fixaudbocf (tcrnjkjigd )
Positive
24 Feb 2022
Not Applicable
41
qrznbeucqc(usjzeylhzg) = kdnswmthpv blerigedea (iyhorqecan )
-
27 Aug 2021
Not Applicable
12
cvluzqppyg(iqupsdhbln) = krxkzvhecy tsvwkwpnoq (epxcmfqlai )
-
28 Aug 2018
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Regulation

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