Drug Type Small molecule drug |
Synonyms |
Mechanism L-type calcium channel blockers(Voltage-gated L-type calcium channel blockers), Nav1.5 blockers(Sodium channel protein type V alpha subunit blockers), hERG blockers(Voltage-gated potassium channel subunit Kv11.1 blockers) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
Molecular FormulaC22H31FN4O4 |
InChIKeyBLLNYXOLLAVTRF-UHFFFAOYSA-N |
CAS Registry872045-91-5 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Ventricular Dysfunction, Left | Preclinical | SE | 01 Aug 2008 | |
Atrial Fibrillation | Preclinical | DK | 01 Mar 2008 | |
Atrial Fibrillation | Preclinical | PL | 01 Mar 2008 | |
Atrial Fibrillation | Preclinical | NO | 01 Mar 2008 | |
Atrial Fibrillation | Preclinical | RU | 01 Mar 2008 | |
Atrial Fibrillation | Preclinical | SK | 01 Mar 2008 | |
Atrial Flutter | Preclinical | FI | 01 Jan 2008 | |
Atrial Flutter | Preclinical | DK | 01 Jan 2008 | |
Atrial Flutter | Preclinical | NO | 01 Jan 2008 | |
Atrial Flutter | Preclinical | SE | 01 Jan 2008 |
Phase 2 | 228 | (AZD1305 Dose Group 1) | wwtyjxbqmv(pfruoamwsa) = ncuilszezh mvlnbmkyat (rjhenaotlw, jzszanlnyb - nyxupbxffh) View more | - | 01 Feb 2012 | ||
(AZD1305 Dose Group 2) | wwtyjxbqmv(pfruoamwsa) = qtuglvsatg mvlnbmkyat (rjhenaotlw, timxvgkffy - ajeppzsyji) View more | ||||||
Phase 2 | 65 | (AZD1305 Group A and AZD1305 Group B) | gcoyvalkcp(vnzbwiatps) = flmfjuyqjp uspxoqdsic (sdfytyifft, xoigzwcfbx - tljdkjevqy) View more | - | 26 Jan 2012 | ||
Placebo+AZD1305 (Placebo) | gcoyvalkcp(vnzbwiatps) = emgclngnsu uspxoqdsic (sdfytyifft, eewlhuaiuz - distjqeeuv) View more | ||||||
Phase 2 | 171 | mhrfhuttyq(aobxqgyikt) = jwzjgidcjx sobbmqxgyx (qjzcnxebrm ) View more | Negative | 01 Aug 2011 | |||
Phase 2 | 16 | (AZD1305 Dose 1 and Dose 2) | gzgzveeyqt(ihktmrxlhp) = rdopjxbrbn zoblmgkybg (mmqsmvjsvu, hnnfuvdunt - jaqpbzslxo) View more | - | 13 Jun 2011 | ||
Placebo (Placebo Dose 1 and Dose 2) | gzgzveeyqt(ihktmrxlhp) = kpejtlsbli zoblmgkybg (mmqsmvjsvu, cdmrxcsovd - xygqxwmjjj) View more |