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Last update 06 May 2025
JSKN016
Last update 06 May 2025
Overview
Basic Info
Drug Type Antibody drug conjugate (ADC) |
Synonyms JSKN016 |
Target |
Action modulators, inhibitors |
Mechanism HER3 modulators(Receptor tyrosine-protein kinase erbB-3 modulators), Trop-2 inhibitors(Tumor-associated calcium signal transducer 2 inhibitors) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Structure/Sequence
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Related
9
Clinical Trials associated with JSKN016NCT06942234
The Multicenter, Open-label, Single-arm, Multi-cohort Phase Ib/II Clinical Study to Evaluate the Efficacy and Safety of JSKN016 in Combination Therapy in Chinese Participants With Inoperable Locally Advanced or Metastatic HER2-negative Breast Cancer
NCT06868732
Evaluation of JSKN016 Combination Therapy in Subjects with Advanced Non-Small Cell Lung Cancer: a Phase Ib Study
NCT06775483
Evaluation of JSKN016 in the Treatment of Advanced Non-small Cell Lung Cance： a Phase II Clinical Study
100 Clinical Results associated with JSKN016
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100 Translational Medicine associated with JSKN016
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100 Patents (Medical) associated with JSKN016
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100 Deals associated with JSKN016
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R&D Status
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Metastatic HER2-Negative Breast Carcinoma | Phase 2 | - | 01 Jun 2025 | |
| HER2-negative breast cancer | Phase 2 | China | 28 Apr 2025 | |
| Adenocarcinoma of Esophagus | Phase 2 | China | 25 Apr 2025 | |
| Advanced Gastroesophageal Junction Adenocarcinoma | Phase 2 | China | 25 Apr 2025 | |
| stomach adenocarcinoma | Phase 2 | China | 25 Apr 2025 | |
| Advanced Lung Non-Small Cell Carcinoma | Phase 2 | China | 20 Dec 2024 | |
| Advanced Malignant Solid Neoplasm | Phase 1 | China | 30 Apr 2024 | |
| Advanced breast cancer | IND Approval | China | 20 Mar 2025 |
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Biosimilar
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Regulation
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