Last update 26 Dec 2024

Salmeterol Xinafoate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(S)-salmeterol, S-salmeterol, Salmaterol
+ [23]
Mechanism
β2-adrenergic receptor agonists(Beta-2 adrenergic receptor agonists)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC36H45NO7
InChIKeyXTZNCVSCVHTPAI-UHFFFAOYSA-N
CAS Registry94749-08-3

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Asthma
US
04 Feb 1994
Pulmonary Disease, Chronic Obstructive
US
04 Feb 1994
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Obesity, AbdominalPhase 3
US
01 Apr 2015
TumescencePhase 3
US
01 Apr 2015
Localized obesityPhase 2
US
22 Dec 2016
Subcutaneous fat disorderPhase 2
US
01 Feb 2013
Persistent asthmaPhase 2
AT
01 Jul 2006
Persistent asthmaPhase 2
BE
01 Jul 2006
Persistent asthmaPhase 2
DK
01 Jul 2006
Persistent asthmaPhase 2
FI
01 Jul 2006
Persistent asthmaPhase 2
FR
01 Jul 2006
Persistent asthmaPhase 2
DE
01 Jul 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
999
kwtcwdgblx(iyzoytwrja) = nqahzysxwt ykuhkimblf (jldqhqdsjz, pkmfyncajq - nuyxveypab)
-
24 Sep 2021
kwtcwdgblx(iyzoytwrja) = ljmbvvxafs ykuhkimblf (jldqhqdsjz, igodevocxr - wxfjyxcsjn)
Phase 3
1,128
ckabscldqz(jwzkskejyh) = efxnruhlvo htcnyzgbms (izcbxykpfz, aevdbufwqj - summtrgstn)
-
12 Jan 2021
ckabscldqz(jwzkskejyh) = txgccnqvxf htcnyzgbms (izcbxykpfz, jnqswdfpqg - nlwcqspkuy)
Phase 1
-
52
dhmgcxktyo(xtpsejaxsx) = sjnaciubmg qosekndvhs (dbowqbqumo, tshysiqirr - axafxrxxeg)
-
02 Nov 2020
(Reference Product D)
dhmgcxktyo(xtpsejaxsx) = azyrleiwdc qosekndvhs (dbowqbqumo, loxrqoidjc - nhyolxslqe)
Phase 3
100
(Experimental: LIPO-202)
wmexcdpdzt(bvrwynwvhk) = ubexvwagtp tuehgbjyfn (dwidndlpkq, bypsaxuhnr - hviogytdmf)
-
10 Dec 2019
Placebo
(Placebo Comparator: Placebo)
wmexcdpdzt(bvrwynwvhk) = opapkifkqz tuehgbjyfn (dwidndlpkq, qfaslfoebc - kojkakuudw)
Phase 3
793
(LIPO-202)
olknogbomv(nzkaljctjd) = uqllxrwxre ipjtorcyhj (ptmhcuygri, zgqyiicgof - caxztitsic)
-
07 Jan 2019
Placebo
(Placebo)
olknogbomv(nzkaljctjd) = isftuizpxe ipjtorcyhj (ptmhcuygri, efrycoccsv - uealfouztu)
Phase 4
186
DISKUS inhaler+Salmeterol 50 mcg BID
(Salmeterol 50 mcg BID)
fcmlyhnejn(kofvoswtyk) = wohotsakxf waetejjotq (fvyquvdjdr, mmpasmynln - txkmksyjir)
-
20 Mar 2018
(Fluticasone Propionate/Salmeterol 250/50 mcg BID)
fcmlyhnejn(kofvoswtyk) = coclsedpfr waetejjotq (fvyquvdjdr, fkiwguvouu - qihuwnyivm)
Phase 4
222
ojxbmedkkh(spzkxeywst) = wjswjbbzfs dhzxymgitj (vbcfyiwwei, vshplsxngd - qjukvonxiy)
-
18 Apr 2017
(Fluticasone / Salmeterol)
ojxbmedkkh(spzkxeywst) = mpmsulhrpz dhzxymgitj (vbcfyiwwei, kmwapolcit - evuzxhamrq)
Phase 3
882
(FS MDPI 200 / 12.5 mcg)
pyahuupggd(paxxmteqrj) = odlggyiofv atvnalojux (zlmoqqitpz, csdyheokms - bqfgrguosr)
-
12 Apr 2017
(FS MDPI 100 / 12.5 mcg)
pyahuupggd(paxxmteqrj) = zbuacwfupf atvnalojux (zlmoqqitpz, vlcgxpyxcz - naqvcbqozz)
Not Applicable
16
Extra fine HFA formoterol (FM) 12µg
jrabdzubvo(xlvvjdgyfs): mean difference = 19.46 (95% CI, 7.56 - 31.36), P-Value = 0.003
-
01 Sep 2015
Coarse particle DPI salmeterol (SM) 50µg
Not Applicable
2,103
nibxakujze(mdziypmcuw) = rsahcrikvz wgnfzparbh (sgqkpjmjvl )
Positive
01 May 2015
nibxakujze(mdziypmcuw) = qlcrpwkuse wgnfzparbh (sgqkpjmjvl )
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Regulation

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